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Evaluation of Femoral Vein Diameter to Predict Intraoperative Hypotension in Geriatric Patients Undergoing Orthopedic Surgery Under Spinal Anesthesia: A Prospective Observational Study
Led by Cairo University · Updated on 2026-01-14
43
Participants Needed
1
Research Sites
N/A
Total Duration
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AI-Summary
What this Trial Is About
This research aims to evaluate whether the transverse diameter of the right common femoral vein (RCFV) measured by ultrasound can predict the degree of low blood pressure (hypotension) during spinal anesthesia in elderly patients undergoing elective orthopedic surgery. Spinal anesthesia often causes hypotension, especially in older adults who have reduced heart and blood vessel function. Previous studies mainly focused on pregnant women having cesarean deliveries, so this study seeks to understand its usefulness in a different high-risk group. Participants will have their RCFV diameter measured 1 cm above the junction with the great saphenous vein at the end of expiration using ultrasound before their surgery. The study involves patients scheduled for elective lower-limb orthopedic surgery under spinal anesthesia. No experimental treatments are given, as this is an observational study assessing the relationship between vein diameter and blood pressure changes. During the study, researchers will monitor blood pressure closely up to 15 minutes after spinal anesthesia to assess the predictive ability of the femoral vein diameter. They will also record the severity of hypotension, any adverse events, and the use of rescue medications during the first 24 hours after surgery. Participants will be observed throughout their surgery and recovery period to collect these measurements. The study will last until July 2026, starting in December 2025.
CONDITIONS
Brief Title
Femoral Vein Diameter to Predict Intraoperative Hypotension in Geriatric Patients Undergoing Orthopedic Surgery Under Spinal Anesthesia
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age greater than 60 years
- American Society of Anesthesiologists (ASA) physical state I or II
- Body mass index (BMI) of 35 kg/m2 or less
- Scheduled for elective lower-limb orthopedic surgery under spinal anesthesia
You will not qualify if you...
- Refusal to participate
- History of psychiatric illness or seizures
- Absolute contraindications to spinal anesthesia including infection at puncture site, severe coagulopathy, anticoagulant use within safety interval, severe hypovolemia, increased intracranial pressure, or allergy to local anesthetics
- Severe cardiac disease such as left ventricular ejection fraction less than 30%, critical aortic stenosis, uncontrolled arrhythmias, or congestive heart failure NYHA class III-IV
- Severe uncontrolled hypertension despite medical therapy
- Severe respiratory diseases including GOLD stage III-IV COPD or forced vital capacity less than 50% predicted
- Baseline bradycardia below 50 bpm or mean arterial blood pressure below 60 mmHg
- Emergency surgeries
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person) for eligibility assessment
Duration - Up to 15 minutes
Participants undergo ultrasound measurement of the right common femoral vein diameter before spinal anesthesia.
1 visit (in-person) on the day of surgery
Duration - 24 hours postoperatively
Participants are observed for intraoperative hypotension during and after spinal anesthesia and monitored for adverse events and medication requirements for 24 hours postoperatively.
Monitoring during surgery and postoperative hospital stay
Trial Site Locations
Total: 1 location
1
Cairo University
Cairo, Egypt, 12613
Actively Recruiting
Research Team
H
Hebatullah S Abdelhamid, MD
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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