Actively Recruiting

Age: 0Hours - 1Hour
All Genders
NCT06186973

Fetal Assessment of the Myocardium and Evaluation of the Neonate

Led by Oslo University Hospital · Updated on 2025-03-18

220

Participants Needed

1

Research Sites

685 weeks

Total Duration

On this page

Sponsors

O

Oslo University Hospital

Lead Sponsor

S

South-Eastern Norway Regional Health Authority

Collaborating Sponsor

AI-Summary

What this Trial Is About

FAME-n aims to improve perinatal care by introducing new approaches to fetal and neonatal heart assessment. Better identification of high-risk deliveries requiring intervention will reduce perinatal asphyxia-related illness and death. Neonatal hemodynamics may be improved by early detection of instability of the heart and circulation. Innovative use of technology enables characterization of normal and abnormal cardiovascular transition in a significantly larger number of fetuses and newborn infants than what was previously possible. The methods used may have broad generalizability and applicability in perinatal, neonatal and pediatric medicine. In September 2023, the project was expanded with an obstetric arm called Epidural analgesia: Fetal Oxygenation and Maternal Oxygenation (Epi-FOMO). In Epi-FOMO, the relationship between maternal breathing and arterial blood gases during labour, and umbilical cord blood gases and neonatal outcomes (as specified in FAME-n) will be investigated.

CONDITIONS

Official Title

Fetal Assessment of the Myocardium and Evaluation of the Neonate

Who Can Participate

Age: 0Hours - 1Hour
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Women admitted for labor and newborn infants included after written consent from both parents if applicable
  • Use of CTG with STAN for fetal monitoring at clinician's discretion
Not Eligible

You will not qualify if you...

  • Perinatal asphyxia requiring therapeutic hypothermia
  • Major malformations or stillbirth
  • Known chromosomal anomalies
  • Congenital heart defects other than patent ductus arteriosus

AI-Screening

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Trial Site Locations

Total: 1 location

1

Oslo University Hospital

Oslo, Norway, 0424

Actively Recruiting

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Research Team

A

Anne Lee Solevåg, MD, PhD

CONTACT

K

Kathrine Samuelsen Hansen, MSc

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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