Actively Recruiting
Fetal Electrophysiologic Abnormalities in High-Risk Pregnancies Associated With Fetal Demise
Led by Medical College of Wisconsin · Updated on 2026-03-04
30
Participants Needed
2
Research Sites
543 weeks
Total Duration
On this page
Sponsors
M
Medical College of Wisconsin
Lead Sponsor
N
National Heart, Lung, and Blood Institute (NHLBI)
Collaborating Sponsor
AI-Summary
What this Trial Is About
Each year world-wide, 2.5 million fetuses die unexpectedly in the last half of pregnancy, 25,000 in the United States, making fetal demise ten-times more common than Sudden Infant Death Syndrome. This study will apply a novel type of non-invasive monitoring, called fetal magnetocardiography (fMCG) used thus far to successfully evaluate fetal arrhythmias, in order to discover potential hidden electrophysiologic abnormalities that could lead to fetal demise in five high-risk pregnancy conditions associated with fetal demise.
CONDITIONS
Official Title
Fetal Electrophysiologic Abnormalities in High-Risk Pregnancies Associated With Fetal Demise
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Current pregnancy complicated by one of the five diagnostic categories: prior unexplained stillbirth at or after 20 weeks gestation, fetal major congenital heart defect, fetal hydrops, fetal gastroschisis, or monochorionic twin pregnancy
- Participant is 18 years of age or older
- Participant speaks English and can read and sign the consent form in English
- Participant can recline comfortably for 1 to 3 hours
- Participant is willing to complete all three procedures (two fetal magnetocardiograms and one neonatal ECG) unless medically unable
- Participant agrees to allow review of prenatal, delivery, and postnatal records to verify diagnosis and clinical findings
You will not qualify if you...
- Severe claustrophobia not improved by breaks, light, or having someone present
- Active labor
- Acute illness
- Unable to recline comfortably with a pillow for more than 1 to 3 hours (with breaks)
- Weight over 450 pounds
- Use of an electric stimulation device (such as TENS unit, pacemaker, or nerve stimulator) that could interfere with recordings, although some devices may still qualify after discussion with study staff
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 2 locations
1
University of Wisconsin - Madison
Madison, Wisconsin, United States, 53715
Actively Recruiting
2
Medical College of Wisconsin
Milwaukee, Wisconsin, United States, 53226
Actively Recruiting
Research Team
M
Mara C Koffarnus, MD
CONTACT
G
Gretchen Eckstein
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
6
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here