What is this study trying to find out about fetal growth?

This study is investigating how reliable measuring the transverse thalamic diameter by ultrasound is for assessing fetal growth and estimating gestational age. Researchers want to understand if this measurement can be a useful growth parameter during pregnancy. The study is sponsored by Cairo University and focuses on improving fetal monitoring methods.

Who may be eligible for this fetal growth clinical trial?

Pregnant women who are female, have a singleton pregnancy between 18 and 36 weeks gestation, and have a first trimester ultrasound with crown-rump length measured may be eligible. Women with certain health conditions like diabetes, hypertension, lupus, or multiple pregnancies are excluded. Please review eligibility criteria for more details.

Is there any cost to participate in this fetal growth clinical trial?

Study-related care, including all ultrasound scans and trial visits, is provided at no cost. Personal travel and other expenses may vary and are not guaranteed to be covered. Participants can expect to attend scheduled ultrasound appointments as part of the study.

Actively Recruiting

FEMALE

Healthy Volunteers

ID07169929

Reliability of Measuring Transverse Thalamic Diameter to Determine Gestational Age as a Fetal Growth Parameter Using 2D Ultrasound

Led by Cairo University · Updated on 2026-03-03

110

Participants Needed

Research Sites

1 weeks

Total Duration

AI-Summary

What this Trial Is About

Researchers are investigating the reliability of measuring the transverse thalamic diameter using 2D ultrasound as a parameter for assessing fetal growth and determining gestational age. The thalamus is a brain structure involved in sensory, motor, and behavioral functions, and its size changes during fetal development. Previous studies have shown correlations between thalamic diameter and gestational age, but more data are needed to clarify its role in fetal growth assessment. The study involves measuring the fetal transverse thalamic diameter via 2D transabdominal ultrasound in pregnant women between 18 and 36 weeks gestation. The measurement is taken at a standard trans-cerebellar plane using a guitar-shaped structure to define the diameter. Alongside this, other biometric measurements such as biparietal diameter, head circumference, abdominal circumference, femur length, and trans-cerebellar diameter are recorded. Gestational age will be calculated based on the thalamic diameter using a published equation. Participants will attend the feto-maternal unit where sonographers will perform ultrasound scans to collect the measurements and exclude congenital anomalies. The primary outcome is to assess the reliability of transverse thalamic diameter as a fetal growth parameter over a six-month period. Safety and growth parameters will be monitored through ultrasound imaging, with participant involvement lasting through the relevant gestational weeks for data collection.

CONDITIONS

Brief Title

Fetal Transverse Thalamic Diameter and Assessment of Gestational Age as a Fetal Growth Parameter Using 2D Ultrasound

Who Can Participate

FEMALE

Healthy Volunteers

Eligibility Criteria

You may qualify if you...

Pregnant women with a singleton pregnancy
Gestational age between 18 and 36 weeks

You will not qualify if you...

Uncertain pregnancy dates without a first trimester ultrasound report with crown-rump length measured
Maternal obesity with BMI greater than 35
Known diabetes mellitus, hypertension, or systemic lupus erythematosus (SLE)
Any fetal head or central nervous system anomalies
Use of maternal opiates or central nervous system drugs such as methadone
Twins or multiple pregnancies

Research Team

Shaimaa El Shemy, MD

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