Actively Recruiting
Fetuin A as a Predictor of Deterioration of Renal Function in Hypertonic Patients
Led by University Hospital Ostrava · Updated on 2023-07-27
200
Participants Needed
1
Research Sites
182 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Commonly used parameters (creatinine, estimated glomerular filtration rate, and urine albumin/creatinine ratio) for prediction of decline of renal function are sensitive for advanced kidney impairment. Modified human urine Fetuin A (urine Fetuin A) with specific modification in urine (Fetuin A) can earlier predict the progression of kidney disease in patients with diabetes. Studies evaluating urine Fetuin A in hypertonic patients are still lacking.
CONDITIONS
Official Title
Fetuin A as a Predictor of Deterioration of Renal Function in Hypertonic Patients
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Have arterial hypertension treated with at least one antihypertensive medication
You will not qualify if you...
- Have diabetes mellitus of any type, defined as fasting glucose >7.0 mmol/l or any glycemia >11.0 mmol/l, or HbA1c >48 mmol/mol
- Have decompensated arterial hypertension defined as office blood pressure >180/110 mmHg or on Ambulatory Blood Pressure Monitoring
- Are receiving renal replacement therapy
- Have rheumatoid diseases such as rheumatoid arthritis, systemic lupus, scleroderma, dermatomyositis, or inflammatory bowel disease, or test positive for antinuclear antibody or extractable nuclear antigen
- Have an acute infection with C-Reactive Protein >50 mg/l
- Have severe liver impairment such as cirrhosis or elevated liver enzymes (ALT or AST >10 μkat/l)
- Have a terminal incurable illness
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University Hospital Ostrava, - Department of Internal Medicine and Cardiology
Ostrava, Czech Republic, Czechia, 70852
Actively Recruiting
Research Team
J
Jiří Hynčica
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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