Actively Recruiting
Fiber Supplementation in Heart Failure With Preserved Ejection Fraction (HFpEF)
Led by University of Michigan · Updated on 2025-07-24
30
Participants Needed
1
Research Sites
139 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The study team is studying how increasing dietary fiber, specifically through adding potato starch to participant's diet, may impact the species of bacteria in participant's gut microbiome. The study team also wants to understand if adding potato starch to participant's diet helps these bacteria make more short chain fatty acids, a byproduct the team thinks may benefit participant's health.
CONDITIONS
Official Title
Fiber Supplementation in Heart Failure With Preserved Ejection Fraction (HFpEF)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Confirmed diagnosis of stable heart failure with preserved ejection fraction (HFpEF) on maximum tolerated heart failure medication without dosage changes in the past month
- Left ventricular ejection fraction greater than 50% documented within the last 12 months
- Confirmed diagnosis of Type II diabetes with glycated hemoglobin less than 10% and no changes in diabetes medication in the past month
You will not qualify if you...
- Current use of prebiotic or probiotic supplements
- Antibiotic use in the past 6 months
- Participation in another interventional clinical trial
- History of allergy to potatoes or potato starch
- History of inflammatory bowel syndrome, inflammatory bowel disease, bowel resection, Roux-en-Y gastric bypass surgery, celiac disease, Crohn's disease, or colorectal cancer
- Hypoglycemic episode with blood glucose below 70 mg/dL in the last month
- Stage IV or V chronic kidney disease
- Pregnancy
- Other serious health conditions limiting life expectancy to less than 12 months
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
University of Michigan
Ann Arbor, Michigan, United States, 48109
Actively Recruiting
Research Team
H
Hayley Billingsley, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
HEALTH_SERVICES_RESEARCH
Number of Arms
1
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