Actively Recruiting
Fibrine Clot-augmented Repair of Longitudinal Meniscus Tears
Led by Ankara City Hospital Bilkent · Updated on 2025-10-02
120
Participants Needed
2
Research Sites
261 weeks
Total Duration
On this page
Sponsors
A
Ankara City Hospital Bilkent
Lead Sponsor
A
Ankara Etlik City Hospital
Collaborating Sponsor
AI-Summary
What this Trial Is About
Longitudinal meniscal tears are a type of meniscal injury characterized by a displaced fragment of the meniscus that flips over into the joint, often resembling a buckle or handle. These tears typically occur in the medial meniscus and are often associated with traumatic knee injuries, particularly in athletes. The displaced meniscal fragment can cause mechanical symptoms such as locking, clicking, or catching of the knee, as well as pain and swelling. If not properly treated, buckle-handle meniscal tears can lead to further complications, including chronic knee instability, increased risk of osteoarthritis, and persistent joint pain.Repairing a longitudinal meniscal tear offers several advantages over partial meniscectomy, particularly in preserving knee function and preventing long-term complications. Meniscal repair aims to restore the integrity of the meniscus, which plays a crucial role in load distribution, shock absorption, and joint stability. Utilizing a fibrin clot during the repair of a buckle-handle meniscal tear can enhance the healing process and improve surgical outcomes. Fibrin clots act as a biological scaffold, promoting tissue regeneration by providing a matrix that facilitates cellular migration and proliferation. The purpose of this study was to compare longitudinal meniscal tear repair reinforced with fibrin clot with routine end-to-end repair in a prospective randomized controlled trial.
CONDITIONS
Official Title
Fibrine Clot-augmented Repair of Longitudinal Meniscus Tears
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Presenting with a painful meniscus (lateral or medial) longitudinal tear
- Aged between 18 and 50 years
- No previous surgery on the same knee
- Able to have an MRI at the end of the first year after surgery
You will not qualify if you...
- Additional collateral ligament damage such as MCL or LCL along with the meniscus tear
- Incomplete clinical scores at the end of the study
- History of previous surgery on the same knee
- Presence of an active infection
- No control MRI performed at the end of the first year
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 2 locations
1
Ankara Bilkent City Hospital
Ankara, Turkey (Türkiye), 06000
Actively Recruiting
2
Ankara Etlik City Hospital
Ankara, Turkey (Türkiye), 06000
Actively Recruiting
Research Team
E
Enejd Veizi, MD
CONTACT
Y
Yasin Erdoğan, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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