Fibrine Clot-augmented Repair of Longitudinal Meniscus Tears - A Prospectively Randomized Controlled Trial

What this Trial Is About

Researchers are evaluating a surgical approach for repairing longitudinal meniscal tears, which are injuries involving a displaced fragment of the meniscus that can cause knee locking, clicking, pain, and swelling. These tears mainly affect the medial meniscus and often follow traumatic knee injuries, especially in athletes. The study compares repair methods to see if adding a fibrin clot can improve healing and outcomes compared to standard meniscal repair. Participants will be randomly assigned to one of two groups: one group will have routine meniscal repair surgery using arthroscopic sutures, while the other group will receive the same repair plus a fibrin clot made from bone marrow aspirate applied between the torn meniscus edges. This clot acts as a biological scaffold to promote tissue healing. Surgeries are performed under spinal anesthesia, and patients will follow the same rehabilitation plan after surgery. Participants will be followed clinically for at least one year, including MRI scans to assess healing of the meniscus. Researchers will also evaluate knee function and activity using scores like the Tegner Activity Scale, KOOS, and Tegner-Lysholm Score at one year. The main outcome is the number of patients with healed menisci on MRI after one year. The study runs from mid-2024 to mid-2029 and is led by Ankara City Hospital Bilkent.

Fibrine Clot-augmented Repair of Longitudinal Meniscus Tears