Actively Recruiting
Fibrinolysis Resistance in Infection and Trauma
Led by Anders Aneman · Updated on 2024-11-08
150
Participants Needed
4
Research Sites
104 weeks
Total Duration
On this page
Sponsors
A
Anders Aneman
Lead Sponsor
L
Liverpool Hospital, South Western Sydney Local Health District
Collaborating Sponsor
AI-Summary
What this Trial Is About
Blood coagulation disorders are often seen in critically ill patients e.g. with severe infection or following extensive injury, that can lead to life threatening events as a result of excessive blood clot formation leading to organ failure. This study aims to use Viscoelastic Testing (VET) technology to detect patients at risk of excessive blood blot formation at the bedside, test new blood coagulation drugs, and guide life-saving use of blood modifying treatments.
CONDITIONS
Official Title
Fibrinolysis Resistance in Infection and Trauma
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults aged 18 years or older
- For sepsis/septic shock group: admitted to ICU needing at least one organ support and mainly for clinically suspected sepsis or septic shock (including SARS-COV-2)
- Expected to stay in ICU and survive beyond the day after next
- For trauma group: trauma as the main diagnosis on ICU admission
- Expected to stay in ICU and survive beyond the day after next
- Receiving respiratory support such as high-flow nasal prongs, non-invasive or invasive ventilation at ICU admission
- Already received or at risk of needing blood transfusion within 24 hours of injury
You will not qualify if you...
- Currently taking oral anticoagulant or antiplatelet therapy
- Not receiving full, active ICU support
- Death expected within 24 hours
- For trauma group: nursing home resident
- Unsurvivable head injury
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 4 locations
1
The Canberra hospital (ICU)
Canberra, Australian Capital Territory, Australia, 2605
Actively Recruiting
2
Liverpool Hospital (ICU)
Liverpool, New South Wales, Australia, 2170
Actively Recruiting
3
Macquarie University Hospital (ICU)
Macquarie, New South Wales, Australia, 2109
Actively Recruiting
4
Royal North Shore Hospital (ICU)
St Leonards, New South Wales, Australia, 2065
Actively Recruiting
Research Team
A
Anders Aneman, MD, PhD, EDIC, FCICM
CONTACT
L
Lucy Coupland, Nurs Cert, BSci (hons), PhD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here