Finnish Venous Ulcer Study Randomized Trial of First-Visit Foam Sclerotherapy Versus Scheduled Treatment for Venous Leg Ulcers

What this Trial Is About

This research aims to assess the impact of first-visit foam sclerotherapy on patients with venous leg ulcers. It compares this approach to the current standard scheduled treatment to determine which leads to faster ulcer healing. The study is based on prior data suggesting potential benefits of early foam sclerotherapy and includes patients with ulcers lasting between one month and one year. Participants are randomly assigned to either receive foam sclerotherapy at their first visit or to follow the scheduled treatment plan. Both groups also receive endothermal ablation and/or foam sclerotherapy during scheduled visits to treat problematic veins related to the ulcer. All participants use class 2 thigh-high compression stockings or the best tolerated compression therapy as part of their care. The treatments focus on insufficient truncal and distal veins. During the study, patients are monitored for up to one year to measure the time it takes for their ulcers to heal. Researchers use duplex ultrasonography to verify vein reflux and assess arterial circulation. Safety and healing progress are carefully tracked, with the primary outcome being the duration until ulcer healing. The total study plans to enroll 248 patients to ensure reliable results.

Finnish Venous Ulcer Study (FINNULCER Study)