Actively Recruiting

Phase Not Applicable
Age: 19Years - 40Years
All Genders
Healthy Volunteers
NCT06711614

FIRE-Diet: Food as an Intervention to Reduce the Effects of Woodsmoke Exposure on Respiratory Health

Led by University of British Columbia · Updated on 2026-02-13

48

Participants Needed

1

Research Sites

236 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Research suggests that consuming more fatty fish, fruits, and vegetables could potentially shield the lungs from the negative impacts of air pollution. The research team will look at whether a dietary intervention aimed at increasing intake of these foods can protect the lungs from woodsmoke as the air pollutant and look into how this works.

CONDITIONS

Official Title

FIRE-Diet: Food as an Intervention to Reduce the Effects of Woodsmoke Exposure on Respiratory Health

Who Can Participate

Age: 19Years - 40Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Healthy, and specifically with no respiratory disease
  • Not taking any supplements, or willing to abstain from supplement use for 4-weeks prior to study start and the whole duration of the study,
  • Must currently consume, on average, less than 2 servings of fish per week and fewer than 5 servings of fruits and vegetables per day based on screening questionnaires.
  • Must have a null GSTM1 genotype determined at screening.
  • Must be able to provide a sufficient sputum sample during the screening visit.
Not Eligible

You will not qualify if you...

  • Pregnant or planning to become pregnant during the study period.
  • Health conditions that would pose an unacceptable risk of dietary change, or conditions that are uncontrolled based on principal investigator's judgement.
  • Actively attempting to lose weight.
  • Frequent wood smoke exposure (e.g. at home or employment).
  • Unable to store provided meals and food safely.
  • Food allergies/intolerance or food aversion preventing adherence to the intervention diet, or unwillingness/medically unable to adjust diet in line with the intervention.
  • Relocation during the study period to an area which will prevent food delivery.
  • History of smoking tobacco, marijuana, or and other substance or vaping within the past 6 months, or having smoked the equivalent of 0.5 pack-years ever.
  • Body mass index (BMI) <18.5, as determined during the in-person screening visit.

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University of British Columbia

Vancouver, British Columbia, Canada, V5Z 1M9

Actively Recruiting

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Research Team

A

Agustin Bueso

CONTACT

A

Agnes Yuen

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

CROSSOVER

Primary Purpose

OTHER

Number of Arms

2

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