Actively Recruiting

Age: 18Years +
All Genders
NCT07249775

A First-in-Human Study of FID-022 in Solid Tumor Patients

Led by H. Lee Moffitt Cancer Center and Research Institute · Updated on 2026-01-28

120

Participants Needed

1

Research Sites

51 weeks

Total Duration

On this page

Sponsors

H

H. Lee Moffitt Cancer Center and Research Institute

Lead Sponsor

F

Florida Cancer Innovation Fund

Collaborating Sponsor

AI-Summary

What this Trial Is About

This observational study aims to (1) validate a multimodal artificial intelligence (AI) model for early detection of cancer-associated cachexia in pancreatic cancer patients and (2) assess the feasibility and acceptability of diet and exercise interventions for cachexia management. The study will use retrospective data from the Florida Pancreas Collaborative and prospective data from newly diagnosed patients at Moffitt Cancer Center.

CONDITIONS

Official Title

A First-in-Human Study of FID-022 in Solid Tumor Patients

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age �318 years
  • Histologically or cytologically confirmed pancreatic exocrine malignancy or clinical features highly suggestive of such malignancy with diagnostic confirmation anticipated during screening or early study period
  • Presentation consistent with resectable, borderline resectable, local, locally advanced, or metastatic disease
  • May or may not have had surgery
  • Treatment plan likely includes systemic therapy for pancreatic cancer
  • ECOG performance status 0-2
  • Able to tolerate oral intake and not currently receiving enteral or parenteral nutrition
  • Able to read and speak English
  • Able to provide written informed consent
Not Eligible

You will not qualify if you...

  • Pregnant or breastfeeding at the time of enrollment
  • Current use of tube feeding (enteral) or total parenteral nutrition
  • Presence of ascites or other findings suggestive of decompensated disease
  • Evidence or history of bowel obstruction or any gastrointestinal condition that may limit food intake
  • Severe or uncontrolled psychiatric illness such as psychosis or dementia that would interfere with participation
  • Presence of other uncontrolled intercurrent illnesses such as infection, heart failure, or liver failure that may interfere with protocol adherence

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Moffitt Cancer Center

Tampa, Florida, United States, 33612

Actively Recruiting

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Research Team

S

Sanjukta Bhattacharjee

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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A First-in-Human Study of FID-022 in Solid Tumor Patients | DecenTrialz