Actively Recruiting
First Observatory of Precocious Puberty.
Led by Hospices Civils de Lyon · Updated on 2026-01-16
3360
Participants Needed
25
Research Sites
208 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The age of puberty has fluctuated throughout history. Recent data shows an increase in the age of onset of puberty signs, in the United States but also in Europe. A recent Public Health France study published in 2018 reports an increase in the incidence of precocious puberty with geographical heterogeneity. The consequences of these appearances include the early onset of menarche, short adult height and the psychological impact. Due to a lack of studies and additional data, the reasons for this development are difficult to understand. Among current hypotheses, the entanglement with the evolution of our environment is at the forefront: the action of environmental endocrine disruptors and nutritional factors could play a role in the process of early appearance of pubertal signs. The establishment of a national observatory for early and advanced puberty in collaboration with pediatric endocrinologists (on the front line) would allow a reliable and precise field approach, capable of supplementing epidemiological data, which are currently insufficient. The investigators hypothesize that the establishment of an observatory of pubertal advances (early puberty and advanced puberty) in private medicine is possible, with inclusion of at least 75% of eligible patients, and collection of at least 80% of data.
CONDITIONS
Official Title
First Observatory of Precocious Puberty.
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Suspected precocious puberty (girl under 8 years or boy under 9 years with first signs of development)
- Suspected advanced puberty (girl aged 8 to under 10 years or boy aged 9 to under 11 years with first signs of development)
- First consultation with the pediatric endocrinologist investigator
- Control group: boy or girl without pubertal signs (Tanner 1), matched by sex and age (+/- 1 year), consulting the same investigator in the same quarter as a PP group patient
You will not qualify if you...
- Families with a language barrier or who do not speak French
- Consultation with the same investigator in the same quarter as a patient in the PP group (applies to all groups)
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 25 locations
1
Clinique du Val d'Ouest
Écully, Auvergne-Rhône-Alpes, France, 69130
Actively Recruiting
2
Clinique du Val d'Ouest
Écully, Auvergne-Rhône-Alpes, France, 69130
Actively Recruiting
3
Clinique du Val d'Ouest
Écully, Auvergne-Rhône-Alpes, France, 69130
Actively Recruiting
4
Pediatric practice
Lyon, Auvergne-Rhône-Alpes, France, 69006
Actively Recruiting
5
Pediatric practice
Rennes, Brittany Region, France, 35200
Actively Recruiting
6
Pediatric practice
Chambray-lès-Tours, Centre-Val de Loire, France, 37170
Actively Recruiting
7
Pediatric practice
Essey-lès-Nancy, Grand Est, France, 54270
Actively Recruiting
8
Pediatric practice
Levallois-Perret, Hauts-de-Seine, France, 92300
Active, Not Recruiting
9
Pediatric practice
Fondettes, Indre-et-Loire, France, 37230
Actively Recruiting
10
Polyclinique Bordeaux rive droite
Lormont, New Aquitaine, France, 33310
Active, Not Recruiting
11
Pediatric practice
Pau, New Aquitaine, France, 64000
Actively Recruiting
12
Pediatric Practice
Pessac, New Aquitaine, France, 33600
Actively Recruiting
13
Clinique rive gauche
Toulouse, Occitanie, France, 31300
Not Yet Recruiting
14
Pediatric practice
Saint-Nazaire, Pays de la Loire Region, France, 44600
Not Yet Recruiting
15
Pediatric practice
Aix-en-Provence, France, 13090
Actively Recruiting
16
Hôpital Femme Mère Enfant, Hospices civils de Lyon
Bron, France, 69677
Actively Recruiting
17
Pediatric practice
Marseille, France, 13008
Active, Not Recruiting
18
Pediatric practice
Marseille, France, 13012
Actively Recruiting
19
Pediatric practice
Nice, France, 06000
Actively Recruiting
20
Clinique Saint jean
Saint-Jean-de-Védas, France, 34430
Active, Not Recruiting
21
Pediatric practice
Trélazé, France, 49800
Actively Recruiting
22
Pediatric practice
Paris, Île-de-France Region, France, 75010
Actively Recruiting
23
Pediatric practice
Paris, Île-de-France Region, France, 75011
Actively Recruiting
24
Pediatric practice
Paris, Île-de-France Region, France, 75017
Actively Recruiting
25
Pediatric practice
Paris, Île-de-France Region, France, 75116
Active, Not Recruiting
Research Team
E
Emillie Doye, MD
CONTACT
T
Tiphanie GINHOUX
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
3
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