Trial Comparing Two Rescue Breathing Devices and Chest Compression Rates in Adults with Out-of-Hospital Cardiac Arrest

What this Trial Is About

Researchers are evaluating basic life support treatments given by Emergency Medical Services EMS first responders to adults who experience sudden out-of-hospital cardiac arrest SCA. The trial compares two rescue breathing methods the standard Bag Valve Mask BVM and the i-gel device. It also studies different chest compression rates during CPR within the recommended range of 100 to 120 compressions per minute. Both treatments are currently used in standard care, and the study aims to see which approach may improve survival to hospital discharge. Participants will be treated by one of 28 EMS agencies randomly assigned to use either the BVM or the i-gel for airway management. These agencies will also be assigned to provide chest compressions at a set rate of either 100, 110, or 120 compressions per minute, guided by a metronome. The study compares these standard-of-care techniques to better understand their effects on patient outcomes. During the study, researchers will track participants from the time of cardiac arrest through hospital discharge, monitoring survival and neurological function. They will observe return of spontaneous circulation shortly after the event and follow survival and neurological status for up to six months. Data on chest compression rates will be electronically recorded to ensure adherence. The total duration of participation varies depending on hospital stay and recovery.

First Responder Airway & Compression Rate Trial