Actively Recruiting
Fisetin in Mild Alzheimer's Disease
Led by Sunnybrook Health Sciences Centre · Updated on 2026-04-13
5
Participants Needed
1
Research Sites
39 weeks
Total Duration
On this page
Sponsors
S
Sunnybrook Health Sciences Centre
Lead Sponsor
S
Sunnybrook Research Institute
Collaborating Sponsor
AI-Summary
What this Trial Is About
This pilot study will evaluate the safety and tolerability of the natural health product, fisetin, in older adults with mild cognitive impairment or mild Alzheimer's disease dementia.
CONDITIONS
Official Title
Fisetin in Mild Alzheimer's Disease
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Mild cognitive impairment due to Alzheimer's disease or mild Alzheimer Dementia
- Moca score of 11 or higher
- Stable psychotropics and cognitive enhancing medications
You will not qualify if you...
- Known hypersensitivity or allergy to fisetin
- Any medical condition or abnormal routine blood test that would put the subject at risk or prevent completing the trial
- Unstable medical disorders
- Ongoing treatment for active infection with antibiotics or antifungals
- Ongoing treatment for cancer
- Active alcohol or substance use disorder
- Recent active bleeding
- Taking oral anticoagulants, anti-cancer, anti-seizure medications, or other drugs that may interact significantly with fisetin
- Use of other senolytic supplements, antioxidant supplements, or natural health products within the last month
- Other neurologic or neurodegenerative conditions affecting cognition
- Active Major Depressive Episode, active suicidal thoughts, or psychosis
- Any condition preventing the ability to undergo an MRI scan
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Sunnybrook Research Institute
Toronto, Ontario, Canada, M4N 3M5
Actively Recruiting
Research Team
S
Study Coordinator
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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