Actively Recruiting
FIT Exercise in 30d of ULLS-induced Muscle Disuse
Led by Lance Bollinger · Updated on 2025-10-24
16
Participants Needed
1
Research Sites
96 weeks
Total Duration
On this page
Sponsors
L
Lance Bollinger
Lead Sponsor
U
University of Louisville
Collaborating Sponsor
AI-Summary
What this Trial Is About
This study aims to determine how flywheel-based inertial training (FIT) implemented according to principles of velocity-based training (VBT) and High-Intensity Interval Training (HIIT) affects disuse-induced physical de-conditioning including loss of voluntary muscle strength, aerobic capacity, and balance regulation.
CONDITIONS
Official Title
FIT Exercise in 30d of ULLS-induced Muscle Disuse
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Regularly engaging in aerobic exercise (> 150 minutes per week) and resistance exercise (at least once per week) for the past 12 months
- Education greater than or equal to bachelor's degree (any field)
You will not qualify if you...
- Waist circumference less than 55 cm or greater than 90 cm for females and less than 75 cm or greater than 100 cm for males
- Body mass index less than 18.5 or greater than 29.9
- Shoe size less than 25 cm or greater than 29 cm
- Not regularly engaging in exercise for the previous 12 months
- Tobacco use within the previous 6 months
- Blood clotting disorder
- Heart arrhythmia
- Implanted device affected by electrical impulses or strong magnetic fields (e.g., pacemaker, internal defibrillator, cochlear implant)
- Diagnosed cardiovascular, pulmonary, renal, or metabolic disease
- Pregnancy within the previous 6 months
- Oral contraceptive use within the previous 3 months
- High resting blood pressure (systolic > 140 and/or diastolic > 90)
- Currently or previously undergone gender-affirming therapy (hormone therapy or sexual reassignment surgery)
- Low back or leg injury within the previous 6 months
- Currently taking medication to assist with sleep
- Muscle, bone, or joint injury limiting physical activity within the previous 6 months
- Neurological disorder affecting balance (such as multiple sclerosis or Parkinson's disease)
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University of Kentucky
Lexington, Kentucky, United States, 40506
Actively Recruiting
Research Team
L
Lance Bollinger, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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