Actively Recruiting

Age: 8Years - 25Years
All Genders
NCT05025774

Fitness and Lung Function Among Survivors of Heart Transplant, Leukemia and Infant BPD Through Exercise

Led by Masonic Cancer Center, University of Minnesota · Updated on 2025-11-24

90

Participants Needed

1

Research Sites

89 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study aims to more accurately assess cardiac function, ventilation and exercise capacity in a non-invasive fashion, and to better characterize exercise intolerance in the setting of three populations of individuals with chronic diseases of childhood (acute lymphoblastic leukemia (ALL), chronic lung disease (CLD) of prematurity, and post-heart transplant (HT))

CONDITIONS

Official Title

Fitness and Lung Function Among Survivors of Heart Transplant, Leukemia and Infant BPD Through Exercise

Who Can Participate

Age: 8Years - 25Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Acute lymphoblastic leukemia survivor, or living with chronic lung disease of prematurity, or living with heart transplant
  • Age between 8 and 25 years old
  • Height at least 48 inches
  • Can walk without assistance
  • Speaks English
  • Blood pressure below the 95th percentile for age (may be controlled with medication)
  • Oxygen saturation (SpO2) above 92%
  • Not pregnant
  • If an ALL survivor, therapy must have been completed at least 3 months before joining the study
  • Controls must have no history of arrhythmia or known heart dysfunction at baseline
  • Controls must have SpO2 above 95%
  • Controls must meet the above age, height, ambulatory, language, blood pressure, and pregnancy requirements
Not Eligible

You will not qualify if you...

  • ALL survivors who have received cranial radiation or bone marrow transplants
  • Investigator or primary doctor considers the participant unsuitable for the study
  • Controls with a history of cancer, chronic lung disease, heart transplant, or other conditions affecting heart or lung function
  • Controls considered unsuitable by the investigator

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Masonic Cancer Center

Minneapolis, Minnesota, United States, 55455

Actively Recruiting

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Research Team

C

Char Napurski, MPH, CCRP

CONTACT

P

Pianosi Paolo, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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Fitness and Lung Function Among Survivors of Heart Transplant, Leukemia and Infant BPD Through Exercise | DecenTrialz