Actively Recruiting
Five Lives MED to Improve Cognitive Function in Mild Cognitive Impairment
Led by SharpTx · Updated on 2025-04-29
170
Participants Needed
7
Research Sites
66 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this randomized controlled trial is to determine whether the digital health app Five Lives MED can improve cognitive function in people with mild cognitive impairment (MCI). The main question it aims to answer is: Can 12 weeks of using Five Lives MED improve global cognitive function in people diagnosed with MCI? Researchers will compare with a control group who receives a leaflet with standard health information. Participants in the intervention group will be asked to use the Five Lives MED app 3 times per week at home for 12 weeks. All participants, in both groups, will undergo cognitive testing and will complete questionnaires at baseline and exit.
CONDITIONS
Official Title
Five Lives MED to Improve Cognitive Function in Mild Cognitive Impairment
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosis of mild cognitive impairment (also known as mild cognitive disorder or mild neurocognitive disorder)
- Age 50 years or older
- Participant or informant willing and able to give informed consent to participate
- Ability to read and understand English (UK) or French (France)
- Access to a mobile phone (Apple iOS 12.4 or above or Android 6.0 or above) or iPad (Apple iOS 12.4 or above) with internet connection
You will not qualify if you...
- Diagnosis of dementia or functional impairment inconsistent with mild cognitive impairment
- Severe visual impairment
- Currently undergoing any other cognitive remediation program
- Currently participating in another investigational study that may affect data integrity
- Physical impairment that makes using a mobile device impossible
- Lack of access to an informant
- Participant under guardianship
- Unwilling or unable to tolerate or engage with study procedures
- Physical impairment that makes standing or walking unassisted impossible
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 7 locations
1
Hôpital Broca, Service de gériatrie Hôpitaux Universitaire Paris Centre, Université Paris Cité
Paris, Île-de-France Region, France, 75013
Not Yet Recruiting
2
Devon Partnership NHS Trust
Exeter, Devon, United Kingdom, EX2 5AF
Actively Recruiting
3
Lancashire & South Cumbria NHS Foundation Trust
Preston, Lancashire, United Kingdom, PR5 6AW
Actively Recruiting
4
Oxford University Hospitals NHS Foundation Trust
Oxford, Oxfordshire, United Kingdom, OX3 9DU
Active, Not Recruiting
5
Somerset NHS Foundation Trust
Taunton, Somerset, United Kingdom, TA1 5DA
Actively Recruiting
6
East London NHS Foundation Trust
London, United Kingdom, E1 8DE
Active, Not Recruiting
7
South London & Maudsley NHS Foundation Trust
London, United Kingdom, SE5 8AF
Active, Not Recruiting
Research Team
J
Jamie Kawadler, PhD
CONTACT
P
Philip Vassilev, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
BASIC_SCIENCE
Number of Arms
2
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