Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
ID04067167

Effects of Flexi Band Resistance Training Versus Different Electromyostimulation Exercise Programs in Patients With the Diagnosis of Malignant Diseases

Led by University of Erlangen-Nürnberg Medical School · Updated on 2026-01-20

100

Participants Needed

1

Research Sites

4 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are evaluating the effects of a 12-week flexi band resistance training program compared to various whole-body electromyostimulation (WB-EMS) exercise programs in patients with malignant diseases undergoing curative or palliative anti-cancer treatment. The study focuses on outcomes such as muscle strength, body composition including muscle mass, cardiorespiratory fitness, inflammation, and patient-reported outcomes like quality of life, fatigue, and performance status. Participants are randomly assigned to one of four groups: low-threshold WB-EMS combined with nutritional therapy, WB-EMS combined with nutritional therapy, free WB-EMS using a mobile system combined with nutritional therapy, or flexi band resistance training combined with nutritional therapy. Each intervention lasts 12 weeks, with patients performing two sessions per week of approximately 20 minutes each, including simple exercises guided by video tutorials. Nutritional therapy involves individualized, protein-rich counseling targeting a protein intake of 1.2 to 1.5 grams per kilogram of body weight per day. During the study, participants will be assessed for muscle strength, muscle mass, fat mass, total body water, cardiorespiratory fitness, inflammation status, and various patient-reported measures such as performance status, quality of life, fatigue, and physical activity. Objective physical activity and cardiometabolic risk profiles will also be monitored at 12 weeks. The study includes regular evaluations to track adherence and safety over the intervention period.

CONDITIONS

Brief Title

Flexi Band Resistance Training Versus EMS Exercise in Patients With the Diagnosis of Malignant Diseases

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosis of malignant disease (solid or hematological cancer) including head and neck cancer, colorectal carcinoma, small intestinal cancer, gastric cancer, oesophageal cancer, pancreas carcinoma, liver cell carcinoma, cholangiocarcinoma, lung cancer, breast cancer, cervix cancer, ovarian cancer, prostate cancer, renal cell carcinoma, malignant melanoma, leukemia, malignant lymphomas, or Graft-versus-Host-Disease after bone marrow transplantation
  • Ongoing or planned curative or palliative anti-cancer therapy
  • ECOG performance status of 0 to 2
  • Adults aged 18 years or older
Not Eligible

You will not qualify if you...

  • Participation in other nutritional or exercise intervention trials simultaneously
  • Bone metastases with high risk of fracture
  • Cardiovascular disease
  • Use of anabolic medications
  • Epilepsy
  • Severe neurological or rheumatic diseases
  • Skin lesions in the area where electrodes would be applied
  • Presence of energy-active metals in the body
  • Pregnancy
  • Acute vein thrombosis

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Treatment

Duration - 12 weeks

Participants undergo 12 weeks of either Whole-Body Electromyostimulation (WB-EMS) or Flexi band resistance training combined with nutritional therapy.

Twice weekly training sessions, approximately 20 minutes each

Trial Site Locations

Total: 1 location

1

Department of Medicine 1, Hector-Center for Nutrition, Exercise and Sports

Erlangen, Germany, 91054

Actively Recruiting

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Research Team

H

Hans Joachim Herrmann, Dr.

Y

Yurdagül Zopf, Prof.

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

4

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