Resistance training for fatigue in people with cancer.
Moritz Ernst, Carina Wagner, Annika Oeser...
https://pubmed.ncbi.nlm.nih.gov/39606939Actively Recruiting
Led by University of Erlangen-Nürnberg Medical School · Updated on 2026-01-20
100
Participants Needed
1
Research Sites
4 weeks
Total Duration
Researchers are evaluating the effects of a 12-week flexi band resistance training program compared to various whole-body electromyostimulation (WB-EMS) exercise programs in patients with malignant diseases undergoing curative or palliative anti-cancer treatment. The study focuses on outcomes such as muscle strength, body composition including muscle mass, cardiorespiratory fitness, inflammation, and patient-reported outcomes like quality of life, fatigue, and performance status. Participants are randomly assigned to one of four groups: low-threshold WB-EMS combined with nutritional therapy, WB-EMS combined with nutritional therapy, free WB-EMS using a mobile system combined with nutritional therapy, or flexi band resistance training combined with nutritional therapy. Each intervention lasts 12 weeks, with patients performing two sessions per week of approximately 20 minutes each, including simple exercises guided by video tutorials. Nutritional therapy involves individualized, protein-rich counseling targeting a protein intake of 1.2 to 1.5 grams per kilogram of body weight per day. During the study, participants will be assessed for muscle strength, muscle mass, fat mass, total body water, cardiorespiratory fitness, inflammation status, and various patient-reported measures such as performance status, quality of life, fatigue, and physical activity. Objective physical activity and cardiometabolic risk profiles will also be monitored at 12 weeks. The study includes regular evaluations to track adherence and safety over the intervention period.
CONDITIONS
Flexi Band Resistance Training Versus EMS Exercise in Patients With the Diagnosis of Malignant Diseases
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Complete this quick 3-step screening to check your eligibility
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 12 weeks
Participants undergo 12 weeks of either Whole-Body Electromyostimulation (WB-EMS) or Flexi band resistance training combined with nutritional therapy.
Twice weekly training sessions, approximately 20 minutes each
Total: 1 location
1
Department of Medicine 1, Hector-Center for Nutrition, Exercise and Sports
Erlangen, Germany, 91054
Actively Recruiting
H
Hans Joachim Herrmann, Dr.
Y
Yurdagül Zopf, Prof.
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
4
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Moritz Ernst, Carina Wagner, Annika Oeser...
https://pubmed.ncbi.nlm.nih.gov/39606939