Study of Telehealth Intervention to Improve Oral and Systemic Health in Cancer Survivors Aged 25 to 75

What this Trial Is About

This research aims to evaluate the effectiveness of a Telehealth Intervention THI in preventing oral complications related to cancer, improving oral health maintenance and oral health-related quality of life, and reducing systemic inflammation compared to usual care among cancer survivors. The study will include 100 cancer survivors, both during active treatment and post-treatment, to assess outcomes such as mucositis, gingival inflammation, tooth decay, and overall quality of life. Participants will be randomly assigned to one of two groups the THI group or the usual care group. The THI group will participate in six monthly virtual sessions that focus on oral health education, self-efficacy, and goal-setting, supported by biweekly text messages. Usual care participants will receive general health-related text messages and a dental resource directory. All participants will undergo intraoral imaging, saliva and blood sample collection, and complete various questionnaires at baseline, 6, and 12 months. Throughout the study, participants will provide saliva and blood samples to measure inflammation markers and oral microbiome profiles. Researchers will collect survey data on health behaviors, quality of life, and clinical characteristics. Intraoral images will be reviewed by dental consultants to monitor oral health changes. The study will track outcomes at baseline, 6, and 12 months to compare oral and systemic health between the two groups and evaluate the impact of the telehealth intervention over time.

F.L.O.S.S. Project (Facilitated Lessons on Oral and Systemic Health in Survivors)