Actively Recruiting

Age: 18Years +
All Genders
NCT06807840

Flu Infection at UPHS

Led by University of Pennsylvania · Updated on 2026-02-05

50

Participants Needed

1

Research Sites

87 weeks

Total Duration

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Sponsors

U

University of Pennsylvania

Lead Sponsor

N

National Institute of Allergy and Infectious Diseases (NIAID)

Collaborating Sponsor

AI-Summary

What this Trial Is About

Cellular and humoral immune responses in individuals with active influenza infection will be assessed. Each year, up to 50 participants will be enrolled. The investigators hypothesize that influenza infection will elicit mostly memory immune responses rather than de novo immune responses to infection.

CONDITIONS

Official Title

Flu Infection at UPHS

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Signed and dated informed consent form provided
  • Willingness to comply with all study procedures and be available for the study duration
  • Age 18 years or older
  • Positive influenza test result from the University of Pennsylvania Health System
Not Eligible

You will not qualify if you...

  • Known allergy to latex
  • Immunosuppression from illness or treatments including chemotherapy or radiation within past 36 months
  • Pregnancy
  • Treatment with immunoglobulin or blood products within 3 months prior to enrollment
  • Any active neoplastic disease or history of hematological malignancy treated within past 5 years
  • Acute or chronic medical conditions that may interfere with immune response evaluation
  • Intent to donate blood during the study period
  • Known infection with HIV, hepatitis B, or hepatitis C
  • Any condition posing unacceptable risk or inability to meet protocol requirements
  • Prolonged inpatient hospitalization that disrupts study procedures
  • Weigh less than 110 pounds

AI-Screening

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Trial Site Locations

Total: 1 location

1

Penn Presbyterian Medical Center

Philadelphia, Pennsylvania, United States, 19104

Actively Recruiting

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Research Team

S

Scott Hensley, PhD

CONTACT

E

Elizabeth Drapeau, PhD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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