Actively Recruiting

Age: 65Years +
All Genders
Healthy Volunteers
NCT06029933

Fluad vs. Fluzone High-Dose Vaccine Effectiveness Among Adults ≥65 Years

Led by Kaiser Permanente · Updated on 2023-09-08

960000

Participants Needed

1

Research Sites

141 weeks

Total Duration

On this page

Sponsors

K

Kaiser Permanente

Lead Sponsor

S

Seqirus

Collaborating Sponsor

AI-Summary

What this Trial Is About

This study will evaluate the relative vaccine effectiveness of quadrivalent adjuvanted inactivated influenza vaccine (aIIV4) versus quadrivalent high-dose inactivated influenza vaccine (HD-IIV4) in preventing polymerase chain reaction (PCR)-confirmed influenza and influenza-related outcomes in adults ≥65 years of age during the 2023/24 and 2024/25 influenza seasons. The study is an observational study conducted at Kaiser Permanente Northern California (KPNC), an integrated health care system in the United States.

CONDITIONS

Official Title

Fluad vs. Fluzone High-Dose Vaccine Effectiveness Among Adults ≥65 Years

Who Can Participate

Age: 65Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Age ≥65 years at the time of influenza vaccination
  • KPNC member at the time of vaccination
  • Receive either aIIV4 or HD-IIV4 at a KPNC facility during the 2023/24 and/or 2024/25 influenza seasons
Not Eligible

You will not qualify if you...

  • Age <65 years at the time of influenza vaccination
  • Received either aIIV4 or HD-IIV4 in the inpatient setting
  • Receive more than one influenza vaccination during a single season period (i.e., 2023/24 or 2024/25 influenza seasons)
  • Receive an influenza vaccination outside of KPNC

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Kaiser Permanente Northern California (entire region)

Oakland, California, United States, 94612

Actively Recruiting

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Research Team

A

Amber H. Hyman, PhD, MPH

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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