Validating a Noninvasive Electric Cardiometry Test to Predict Fluid Responsiveness in Critically Ill Children in Intensive Care

What this Trial Is About

Researchers are evaluating a faster, simpler, and noninvasive method to assess fluid responsiveness in critically ill children with circulatory failure. The study aims to validate a test based on the effects of a standardized abdominal compression measured by electrical cardiometry, to help doctors identify which patients might benefit from fluid expansion and avoid harmful fluid overload. This observational, multi-center study focuses on children prescribed a 10 mlkg volume expansion for circulatory failure in pediatric intensive care units. The study involves performing a standardized abdominal compression maneuver using a sphygmomanometer inflated with 80 ml of air, applying gentle pressure on the patients abdomen. Stroke volume variation induced by this maneuver is measured continuously with electrical cardiometry, a noninvasive cardiac output monitor. Echocardiography assessments are conducted before and within one hour after fluid expansion to measure stroke volume changes as the gold standard for fluid responsiveness. No additional blood tests or invasive procedures are performed. Participants will undergo echocardiographic and electrical cardiometry evaluations around the time of their prescribed fluid expansion, with monitoring continuing until discharge from the pediatric intensive care unit or up to 28 days. Researchers will analyze the diagnostic accuracy of the abdominal compression test in predicting a 15% or greater increase in stroke volume after fluid expansion. The main outcome measure is the area under the ROC curve for stroke volume variation induced by abdominal compression compared to echocardiographic results.

Fluid-responsiveness Assessment Simplified by Electric Cardiometry in Children