Actively Recruiting

Phase 2
Age: 18Years +
All Genders
NCT05965817

Fluorescence-guided Resection Of Colorectal Liver Metastases Using SGM-101 and Indocyanine GREEN

Led by Leiden University Medical Center · Updated on 2024-05-09

10

Participants Needed

1

Research Sites

73 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This will be the first trial testing the feasibility of working simultaneously with the two fluorescent dyes ICG and SGM-101 in 10 patients with colorectal metastases.

CONDITIONS

Official Title

Fluorescence-guided Resection Of Colorectal Liver Metastases Using SGM-101 and Indocyanine GREEN

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosed with liver metastases from colorectal cancer and scheduled for surgical removal
  • Scheduled for surgery involving more than 3 colorectal liver metastases, or
  • Completed neoadjuvant chemotherapy with the last course within 3 months before surgery, or
  • Scheduled for surgery due to a locally recurrent liver metastasis
  • Age 18 years or older
  • Willing and able to provide informed consent before study procedures
Not Eligible

You will not qualify if you...

  • History of anaphylactic shock
  • Pregnancy or breastfeeding (pregnancy must be ruled out by a test within 2 weeks before study drug administration)
  • Known positive test for HIV, hepatitis B surface antigen, or hepatitis C antibody, or untreated serious infections
  • Previous treatment with SGM-101
  • Allergies to shellfish or clamps
  • Hyperthyroidism
  • Known allergy to indocyanine green (ICG)
  • Any condition that may jeopardize patient safety or study objectives as judged by the investigator

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Leiden University Medical Center

Leiden, Netherlands, 2333ZA

Actively Recruiting

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Research Team

M

Mats Warmerdam, Msc

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

DIAGNOSTIC

Number of Arms

1

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Fluorescence-guided Resection Of Colorectal Liver Metastases Using SGM-101 and Indocyanine GREEN | DecenTrialz