Actively Recruiting
Fluorescence Lymph Node Mapping for Colon Cancer Surgery
Led by Pusan National University Yangsan Hospital · Updated on 2025-07-11
186
Participants Needed
13
Research Sites
283 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Fluorescence-guided surgery using indocyanine green can visualize the complex and diverse lymph node drainage structures for each patient and help determine the extent of dissection of the D3 lymph node tailored to the patient. However, since fluorescence lymph node mapping (FLNM) is still being conducted only at some institutions for research purposes and is limited to reporting the results of small-scale studies of patients, a large-scale multi-center study was conducted to verify the clinical-oncological effects of FLNM. Research is needed. Therefore, this study used real-time fluorescence lymph node mapping (FLNM) to determine the extent of D3 lymph node dissection when performing right hemicolectomy and D3 lymph node dissection in patients with locally advanced right-sided colon cancer and to safely remove extensive lymph nodes. We aim to evaluate whether the dissection procedure is safe and beneficial in terms of clinical oncology.
CONDITIONS
Official Title
Fluorescence Lymph Node Mapping for Colon Cancer Surgery
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients aged 19 to 85 years
- Locally advanced right-sided colon cancer requiring D3 lymphadenectomy
- Clinical stage cT3-4 N0 or cTany N1-2 diagnosed before surgery
- Cancer located in the cecum, ascending colon, flexure colon, or proximal transverse colon
- American Society of Anesthesiology (ASA) physical status I to III
- Provided informed consent and agreed to participate in the research
You will not qualify if you...
- Allergy or side effects to sodium iodine
- Presence of distant or peritoneal metastases from colon cancer
- Need for emergency surgery due to colon obstruction or perforation
- Uncontrolled inflammatory bowel disease
- Presence of other cancers outside the colon
- History of hereditary disease or bleeding disorders
- Pregnancy, possible pregnancy, or lactation
- Chronic renal failure with e-GFR less than 15 or receiving dialysis
- Liver failure or decreased consciousness from hepatic encephalopathy
- Recent heart disease causing lymph perfusion difficulty (within 6 months)
- Unable to undergo general anesthesia
- American Society of Anesthesiology (ASA) physical status IV or V
- Declined participation in this study
- Judged unsuitable by researchers due to low life expectancy or compliance issues
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 13 locations
1
Keimyung University Dongsan Medical Center
Daegu, South Korea
Not Yet Recruiting
2
Kyungpook National University Chilgok Hospital
Daegu, South Korea
Actively Recruiting
3
Chungnam National University Hospital
Daejeon, South Korea
Actively Recruiting
4
National Cancer Center Korea
Goyang, South Korea
Not Yet Recruiting
5
Chonnam National University Hwasun Hospital
Hwasun, South Korea
Actively Recruiting
6
Gachon University Gil Medical Center
Incheon, South Korea
Actively Recruiting
7
Jeonbuk National University Hospital
Jeonju, South Korea
Actively Recruiting
8
Seoul National University Bundang Hospital
Seongnam, South Korea
Not Yet Recruiting
9
Asan Medical Center
Seoul, South Korea
Actively Recruiting
10
Korea University Guro Hospital
Seoul, South Korea
Not Yet Recruiting
11
Kyung Hee University Hospital
Seoul, South Korea
Not Yet Recruiting
12
St. Vincent's Hospital, The Catholic University of Korea
Suwon, South Korea
Actively Recruiting
13
Pusan National University Yangsan Hospital
Yangsan, South Korea
Actively Recruiting
Research Team
P
Principal Investigator, PhD
CONTACT
P
Principal Investigator, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
DIAGNOSTIC
Number of Arms
2
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