Actively Recruiting
fMRI Accelerated TMS Depression
Led by Medical University of South Carolina · Updated on 2025-10-16
20
Participants Needed
1
Research Sites
97 weeks
Total Duration
On this page
Sponsors
M
Medical University of South Carolina
Lead Sponsor
F
Foundation for the Advancement of Clinical TMS
Collaborating Sponsor
AI-Summary
What this Trial Is About
This study aims to investigate whether phenotypic-related brain states revealed by a novel INSCAPE ("Individualized Network-based Single-frame Coactivation Pattern Estimation") neuroimaging method in Major Depressive Disorder (MDD) patients can track brain recovery of MDD patients over an accelerated antidepressant transcranial magnetic stimulation (TMS) treatment.
CONDITIONS
Official Title
fMRI Accelerated TMS Depression
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18-65
- Ability to provide informed consent in English
- Diagnosis of Major Depressive Disorder (MDD) according to DSM-IV
You will not qualify if you...
- Unable to speak English
- Contraindicated for MRI
- Current or recent untreated medical, neurological, or psychiatric conditions
- Metal implant devices in head, heart, or neck
- History of brain surgery
- History of cortisol medication use or electroconvulsive therapy
- Comorbidity with other psychiatric or neurological illnesses or personality disorders
- History of myocardial infarction, arrhythmia, or bradycardia
- History of head injury, concussion, or moderate to severe traumatic brain injury
- Frequent or severe headaches
- Moderate to severe alcohol or substance use disorder
- Pregnancy
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
30 Bee Street
Charleston, South Carolina, United States, 29429
Actively Recruiting
Research Team
M
Marion Wood
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here