Functional Magnetic Resonance Imaging Findings and Symptoms in Bladder Pain Syndrome: A Descriptive Study

What this Trial Is About

This research aims to understand how brain activity, shown through functional magnetic resonance imaging (fMRI), relates to symptoms in people with bladder pain syndrome (BPS). The study will explore where brain changes occur in these patients and seek clues to better understand the causes and possible treatments of BPS. It includes patients with and without urinary tract infections to compare findings. Participants will undergo one fMRI scan using a Siemens 3.0T MRI scanner with specific imaging sequences to capture brain function. Along with the fMRI, routine lab tests like urine analysis and ultrasound, and symptom questionnaires including pain scales and depression and anxiety assessments, will be completed. The study collects data during an initial screening visit and a follow-up visit after enrollment. During the study, participants will provide medical history, complete symptom and mood questionnaires, and undergo urine tests and bladder function assessments. Researchers will analyze fMRI brain images alongside symptom scores to identify brain regions linked to pain. The primary outcome is the fMRI findings from one scan per participant. Data management includes careful entry, verification, and long-term storage. Participation involves two visits and monitoring of symptoms and brain activity.

fMRI for BPS: A Descriptive Study of Findings and Symptoms