Actively Recruiting

Phase Not Applicable
Age: 18Years - 30Years
All Genders
Healthy Volunteers
NCT07332962

fMRI Evaluation of Auricular Acupuncture Targets: An Exploratory Clinical Study

Led by Jiangsu Taizhou People's Hospital · Updated on 2026-01-12

32

Participants Needed

1

Research Sites

5 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study employs resting-state functional magnetic resonance imaging (rs-fMRI) to examine whether auricular press needles acupuncture modulates functional connectivity between the insula and medial prefrontal cortex (MPFC), in a manner comparable to transcranial vagus nerve stimulation (taVNS), and to assess its association with interoceptive improvement. By establishing a neurophysiological baseline for auricular vagus nerve stimulation (aVNS) in the healthy brain, the research aims to clarify its regulatory mechanisms in cognition and emotion. The findings provide a key theoretical and evaluative framework for translating aVNS into clinical applications for insomnia and depression.

CONDITIONS

Official Title

fMRI Evaluation of Auricular Acupuncture Targets: An Exploratory Clinical Study

Who Can Participate

Age: 18Years - 30Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Age between 18 and 30 years
  • Basically normal diet and sleep
  • No history of mental illness
  • No contraindications for MRI such as metal implants, pacemakers, or claustrophobia
  • Willing to participate and able to sign informed consent
Not Eligible

You will not qualify if you...

  • Presence of skin lesions on the ear or allergy to adhesive ear patches
  • Currently receiving regular acupuncture treatment
  • History of bleeding disorders or use of anticoagulants
  • Previous history of fainting during acupuncture

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Taizhou People's Hospital affiliated to Nanjing Medical University

Taizhou, Jiangsu, China, 225300

Actively Recruiting

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How is the study designed?

Study Type

INTERVENTIONAL

Masking

TRIPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

HEALTH_SERVICES_RESEARCH

Number of Arms

2

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