Actively Recruiting
Focal Ablation With Focal Cryotherapy or HIFU for the Treatment of Men With Localized Prostate Cancer
Led by Marc Dall'Era, MD · Updated on 2024-12-16
100
Participants Needed
1
Research Sites
290 weeks
Total Duration
On this page
Sponsors
M
Marc Dall'Era, MD
Lead Sponsor
N
National Cancer Institute (NCI)
Collaborating Sponsor
AI-Summary
What this Trial Is About
This clinical trial evaluates the effectiveness of focal ablation with either focal cryotherapy or high intensity frequency ultrasound for the treatment of men with localized prostate cancer. Focal cryotherapy kills tumor cells by freezing them. High intensity frequency ultrasound uses highly focused ultrasound waves to produce heat and destroy tumor cells.
CONDITIONS
Official Title
Focal Ablation With Focal Cryotherapy or HIFU for the Treatment of Men With Localized Prostate Cancer
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Ability to understand and willing to sign informed consent
- Clinically localized grade group 1, 2, or 3 prostate cancer with unilateral MRI-visible lesion(s) up to 3 lesions
- Eastern Cooperative Oncology Group (ECOG) performance status of 1 or less (Karnofsky score 70% or higher)
- Men aged 18 years or older at consent
- Life expectancy of 5 years or more
- Willing and able to follow study visit schedule and procedures for the study duration
You will not qualify if you...
- Presence of nodal or distant metastases
- Prior treatment for prostate cancer
- Planned cancer treatment including radiation, hormonal therapy, or surgery within 6 months before focal therapy
- Known contraindications to general anesthesia
- Uncorrectable bleeding disorders
- Significant active cardiac disease within the last 6 months such as NYHA class 4 congestive heart failure, unstable angina, or recent myocardial infarction
- Any condition preventing informed consent
- Any condition that may interfere with safety or compliance during the trial
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University of California Davis Comprehensive Cancer Center
Sacramento, California, United States, 95817
Actively Recruiting
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here