Actively Recruiting

Phase 2
Phase 3
Age: 45Years - 55Years
FEMALE
Healthy Volunteers
NCT06975111

Focusing on the Menopausal Transition to Improve Mid-Life Women's Health

Led by University of Colorado, Denver · Updated on 2026-04-30

200

Participants Needed

1

Research Sites

239 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

What if midlife women, who are inherently at an increased risk for future cardiometabolic disease due to transitioning into menopause, had access to a suite of evidence-based health interventions? Could these interventions reduce menopause-related inflammation, restore a healthier cardiometabolic profile, reverse epigenetic aging, and reduce bothersome menopausal symptoms? The ultimate goal of this work is to attenuate future disease and enhance women's quality of life, extend healthspan and increase productivity.

CONDITIONS

Official Title

Focusing on the Menopausal Transition to Improve Mid-Life Women's Health

Who Can Participate

Age: 45Years - 55Years
FEMALE
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Aged 45 to 55 years
  • In the late menopausal transition, defined as 60 days of amenorrhea but less than 365 days of amenorrhea
  • No current use of hormone therapy or hormonal contraception
  • Presence of a uterus and at least one ovary to track menstrual patterns
  • Have a smartphone and broadband access adequate for telehealth appointments
Not Eligible

You will not qualify if you...

  • Lack of broadband access
  • Lack of regular menstrual periods in mid-reproductive life (ages 25-38) when not on hormones or pregnant
  • Pregnancy or actively trying to get pregnant
  • Inability to follow the study protocol schedule
  • Untreated alcoholism
  • Undiagnosed abnormal uterine bleeding
  • Personal or family history of medullary thyroid cancer or multiple endocrine neoplasia (MEN 2) if BMI over 30 kg/m2

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
+1

Trial Site Locations

Total: 1 location

1

University of Colorado-School of Medicine

Aurora, Colorado, United States, 80045

Actively Recruiting

Loading map...

Research Team

C

Carrie Hsu, BA

CONTACT

N

Nalia Naushad

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NON_RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

5

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here

Focusing on the Menopausal Transition to Improve Mid-Life Women's Health | DecenTrialz