Actively Recruiting
Folic Acid Supplement Versus Placebo for Treating Mucositis Adverse Events in Metastatic Renal Cell Carcinoma Patients Receiving Targeted Therapy
Led by Niels Fristrup · Updated on 2026-05-04
100
Participants Needed
2
Research Sites
610 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
FASTERCC: Folic acid supplement versus placebo for treating mucositis adverse events in metastatic renal cell carcinoma patients receiving targeted therapy. A randomized, double-blind trial from the Danish renal cancer group (DARENCA study-4)
CONDITIONS
Official Title
Folic Acid Supplement Versus Placebo for Treating Mucositis Adverse Events in Metastatic Renal Cell Carcinoma Patients Receiving Targeted Therapy
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients with inoperable, locally advanced, or metastatic renal cell carcinoma confirmed by biopsy
- Displaying CTCAE grade 2 or higher mucositis during TKI, mTOR inhibitor, or immunotherapy treatment
- Signed written informed consent before any study procedures
- Age 18 years or older
- Females with negative serum pregnancy test unless childbearing potential is excluded (postmenopausal, hysterectomy, or oophorectomy) and not breastfeeding
- Fertile women of childbearing potential and men must use effective contraception
- Karnofsky Performance Status of 60% or higher
You will not qualify if you...
- Known allergy or hypersensitivity to folic acid
- Use of prednisolone more than 10 mg daily
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 2 locations
1
Aarhus University Hospital, Department of oncology
Aarhus, Central Region of Denmark, Denmark, 8000
Actively Recruiting
2
Department of Oncology, Herlev Hospital
Herlev, Denmark, 2730
Actively Recruiting
Research Team
N
Niels Fristrup, MD PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here