Actively Recruiting
Follicular Fluid Exosome miRNA During Oocyte Maturation
Led by Chinese University of Hong Kong · Updated on 2025-08-13
60
Participants Needed
1
Research Sites
260 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Folliculogenesis involves the recruitment of primordial follicles into a group of growing follicles in which eventually one follicle is selected, matured and ovulated. Complex endocrine and intra-ovarian paracrine interactions occur to create a changing intra-follicular hormonal milieu suitable for oocyte development. However, this oocyte developmental competence and to undergo fertilization and embryogenesis is impaired in aged women. Diminished ovarian function is generally attributed to decreased quantity and quality of oocytes and their surrounding granulosa cells during ovarian aging, although the underlying mechanisms remain unclear. The aim of the study is to investigate the miRNA in (follicular fluid) FF exosome in young and aged women and their relationship to egg maturation.
CONDITIONS
Official Title
Follicular Fluid Exosome miRNA During Oocyte Maturation
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Women aged 20 to 45
- BMI greater than 19 and less than 35
- Women planning to undergo in vitro fertilization (IVF) with intracytoplasmic sperm injection (ICSI) for fertility problems
You will not qualify if you...
- Positive pregnancy test before starting study procedures
- BMI greater than 35
- Known chromosomal translocation, recurrent abortions, or carrying Fragile X
- Diagnosis of endometriosis
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
The Chinese University of Hong Kong
Hong Kong, Hong Kong
Actively Recruiting
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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