Actively Recruiting
Follicular Fluid microRNAs in Ovarian Aging and Reproduction
Led by University of Central Florida · Updated on 2025-10-09
100
Participants Needed
1
Research Sites
49 weeks
Total Duration
On this page
Sponsors
U
University of Central Florida
Lead Sponsor
T
The IVF Center at Winter Park
Collaborating Sponsor
AI-Summary
What this Trial Is About
The purpose of this study is to investigate the role of exosomal microRNAs (miRNAs) in follicular fluid (FF) as biomarkers of ovarian aging and predictors of in vitro fertilization (IVF) outcomes. The goal is to identify noninvasive molecular markers that correlate with oocyte quality and reproductive potential, particularly in women of advanced maternal age.
CONDITIONS
Official Title
Follicular Fluid microRNAs in Ovarian Aging and Reproduction
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Women undergoing IVF treatment due to male factor infertility or nonovarian causes.
- Age groups: younger women <31 years and older women >38 years.
- Regular menstrual cycles.
- Willing and able to provide informed consent.
You will not qualify if you...
- Minors (under 18 years) and women aged 32-37 years.
- Diagnosis of polycystic ovarian syndrome (PCOS).
- History of recurrent pregnancy loss.
- Presence of endometriosis.
- Diagnosis of ovarian insufficiency.
- Metabolic disorders (e.g., diabetes).
- History of ovarian surgery or chemotherapy.
- Any condition that might impact follicular fluid quality or IVF outcomes.
AI-Screening
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Trial Site Locations
Total: 1 location
1
University of Central Florida
Orlando, Florida, United States, 32827
Actively Recruiting
Research Team
A
Amoy Fraser, PhD, CCRP, PMP
CONTACT
B
Britney-Ann Wray, BS, CTBS, CCRP
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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