Actively Recruiting

Phase Not Applicable
Age: 0 - 18Years
All Genders
ID05471908

The Follow-up Automatically vs. As-Needed Comparison Trial for Children Hospitalized with Common Infections

Led by University of Utah · Updated on 2025-12-10

2674

Participants Needed

14

Research Sites

56 weeks

Total Duration

On this page

Sponsors

U

University of Utah

Lead Sponsor

P

Patient-Centered Outcomes Research Institute

Collaborating Sponsor

AI-Summary

What this Trial Is About

This research aims to compare two different approaches to post-hospitalization follow-up care for children hospitalized with common infections such as pneumonia, skin and soft tissue infections, acute gastroenteritis, or urinary tract infections. The study evaluates whether automatic follow-up visits scheduled at discharge or a more flexible as-needed (PRN) follow-up approach, where parents monitor symptoms and decide on visits, impact hospital readmission rates and other health outcomes. Participants are randomly assigned to one of two groups. One group receives a recommendation for automatic follow-up, instructing them to schedule and attend a follow-up visit regardless of symptom improvement. The other group receives a recommendation for PRN follow-up, where scheduling a visit at discharge is not required, and parents decide if a visit is necessary based on their child's symptoms. Both groups are monitored to compare outcomes over time. During the study, researchers will track hospital readmissions within 14 days of discharge as the primary outcome. Secondary outcomes include medical interventions and the child's health-related quality of life measured seven days after discharge. Additional factors like healthcare use, parent anxiety, satisfaction, and costs will also be assessed. The study includes follow-up through communications with healthcare providers and monitoring of immunizations and well-child visits. Participation lasts at least through the 14-day post-discharge period to capture these outcomes.

CONDITIONS

Brief Title

Follow-up Automatically vs. As-Needed Comparison (FAAN-C) Trial

Who Can Participate

Age: 0 - 18Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Child is younger than 18 years at the time of randomization
  • Hospitalized for pneumonia, skin and soft tissue infection, acute gastroenteritis, or urinary tract infection
  • Parent or guardian speaks English or Spanish
Not Eligible

You will not qualify if you...

  • Has a chronic and complex medical condition
  • Illness required surgery beyond simple incision and drainage
  • Has immunodeficiency
  • Already has a scheduled well-child check-up or follow-up visit within 7 days of discharge
  • Parent or participant strongly prefers one follow-up method
  • Medical provider strongly recommends a follow-up visit within 7 days
  • Has a sibling hospitalized at the same time
  • No clinic identified for follow-up care
  • Pneumonia complicated by chest tube use
  • Urinary tract infection complicated by neurogenic bladder, urologic surgery, planned renal imaging within 7 days, or renal abscess
  • Skin or soft tissue infection complicated by chronic wound, postoperative infection, poor wound healing, drain in place, necrotizing fasciitis, or toxic shock syndrome
  • Gastroenteritis complicated by hemolytic uremic syndrome

AI-Screening

AI-Powered Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person or remote) for eligibility assessment

Post-hospitalization Follow-up

Duration - Up to 14 days after hospital discharge

Participants receive a recommendation for either automatic or as-needed (PRN) follow-up after hospital discharge and monitor their child's symptoms accordingly.

1 follow-up visit recommended for automatic group; as-needed follow-up visits for PRN group

Trial Site Locations

Total: 14 locations

1

Phoenix Children's Hospital

Phoenix, Arizona, United States, 85016

Actively Recruiting

2

Packard at El Camino Hospital

Mountain View, California, United States, 94040

Actively Recruiting

3

Lucile Packard Children's Hospital

Palo Alto, California, United States, 94304

Actively Recruiting

4

St. Louis Children's Hospital

St Louis, Missouri, United States, 63110

Actively Recruiting

5

Penn Medicine Princeton Medical Center

Plainsboro, New Jersey, United States, 08536

Actively Recruiting

6

Cincinnati Children's Hospital Medical Center - Main Campus

Cincinnati, Ohio, United States, 45229

Actively Recruiting

7

Cincinnati Children's Hospital Medical Center - Liberty Campus

Liberty Township, Ohio, United States, 45044

Actively Recruiting

8

Children's Hospital of Philadelphia

Philadelphia, Pennsylvania, United States, 19104

Actively Recruiting

9

Texas Children's Main

Houston, Texas, United States, 77030

Actively Recruiting

10

Texas Children's West

Houston, Texas, United States, 77094

Actively Recruiting

11

Intermountain Primary Children's Hospital Larry H. and Gail Miller Family Campus

Lehi, Utah, United States, 84043

Actively Recruiting

12

Riverton Hospital

Riverton, Utah, United States, 84065

Completed

13

Primary Children's Hospital

Salt Lake City, Utah, United States, 84113

Actively Recruiting

14

Seattle Children's Hospital

Seattle, Washington, United States, 98105

Actively Recruiting

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Research Team

E

Eric Coon, MD, MS

L

Liz Rodriquez

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

HEALTH_SERVICES_RESEARCH

Number of Arms

2

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