Actively Recruiting

Age: 3Months - 80Years
All Genders
NCT05329350

Follow-up Study to Monitor the Efficacy and Safety of the Occlutech® mVSD Cases

Led by Occlutech International AB · Updated on 2026-02-02

50

Participants Needed

5

Research Sites

395 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The Occlutech® mVSD is indicated for percutaneous occlusion of hemodynamically or clinically significant muscular ventricular septal defects. The objectives of the study are: * To confirm the efficacy of Occlutech mVSD in patients requiring transcatheter occlusion (closure) of muscular ventricular septal defects. * To confirm the safety of Occlutech mVSD in patients requiring transcatheter occlusion (closure) of muscular ventricular septal defects.

CONDITIONS

Official Title

Follow-up Study to Monitor the Efficacy and Safety of the Occlutech® mVSD Cases

Who Can Participate

Age: 3Months - 80Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Indicated for percutaneous closure of hemodynamically or clinically significant muscular ventricular septal defects as per device instructions
  • Any age
  • Male or female
  • Understands the study and provides informed consent
  • Willing and able to attend all follow-up visits and procedures required by the study
Not Eligible

You will not qualify if you...

  • Hemodynamically relevant VSD shunt
  • Congestive heart insufficiency
  • Recurrent respiratory infections
  • Failure to thrive
  • Significant left ventricle enlargement
  • Significant left atrium enlargement
  • Active bacterial infection at implantation
  • Allergy to antiplatelet or anticoagulant therapy
  • Allergy to nickel, titanium, or nickel/titanium-based materials
  • Serious infection within 1 month before procedure
  • Aortic rim less than 2 mm
  • Intracardiac thrombi seen on echocardiography
  • Malignancy with life expectancy under 3 years
  • mVSD diameter greater than 20 mm
  • Perimembranous VSD
  • Recent myocardial infarction or bypass surgery within 30 days
  • Local or generalized sepsis
  • Septal thickness greater than 7 mm at device placement area

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 5 locations

1

Children's Health Ireland

Dublin, Ireland, N512

Not Yet Recruiting

2

İzmir Şehir Hastanesi

Izmir, Bayraklı, Turkey (Türkiye), 35540

Not Yet Recruiting

3

Eskişehir Osmangazi Üniversite Hastanesi

Eskişehir, Odunpazarı, Turkey (Türkiye), 26040

Not Yet Recruiting

4

Dicle Üniversitesi Tıp Fakültesi Hastanesi

Diyarbakır, Sur, Turkey (Türkiye)

Not Yet Recruiting

5

Gaziantep Unıversıty Hospital

Gaziantep, Şehitkamil, Turkey (Türkiye), 27310

Actively Recruiting

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Research Team

A

Ahmed Della

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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