Actively Recruiting
Food Challenge at Home or in Medical Practice - the FoodCHOMP Study
Led by Austin Health · Updated on 2025-04-17
120
Participants Needed
2
Research Sites
84 weeks
Total Duration
On this page
Sponsors
A
Austin Health
Lead Sponsor
R
Royal Melbourne Hospital, Australia
Collaborating Sponsor
AI-Summary
What this Trial Is About
This is a pilot, multi-centre, randomised clinical trial evaluating the safety and feasibility of a home-based oral food challenge in adults with low-risk food allergy labels. Eligible participants are aged 18 years or older and have a self-reported food allergy with negative skin prick testing to the implicated food. Participants will be randomised to either a home-based or standard in-clinic food challenge. The primary aim is to determine the safety of home challenges, measured by the rate of immune-mediated adverse events. Secondary aims include feasibility of recruitment and delivery, protocol adherence, quality of life, and food reintroduction outcomes.
CONDITIONS
Official Title
Food Challenge at Home or in Medical Practice - the FoodCHOMP Study
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Negative (less than 3mm) skin test to the food involved in your allergy label
- Aged over 18 years
You will not qualify if you...
- Evidence of prior sensitisation to the challenge food such as previous positive skin test or specific IgEs
- Pregnancy
- Poorly controlled asthma defined by ACQ5 score greater than 1 at enrolment
- History of food reactions not consistent with IgE allergy, such as only gastrointestinal symptoms or FPIES
- History of food-dependent exercise induced anaphylaxis
- Use of medications that may affect challenge outcome including antihistamines, high dose steroids (over 50mg QID hydrocortisone or equivalent), or Omalizumab
- Any other illness that increases risk for participation as judged by the investigator
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 2 locations
1
Austin Health
Melbourne, Victoria, Australia
Actively Recruiting
2
Royal Melbourne Hospital
Melbourne, Victoria, Australia
Actively Recruiting
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
DIAGNOSTIC
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here