Study of Food Effects on Metabolism and Thermogenesis in Men with High Spinal Cord Injury Including Men Without Spinal Cord Injury as Controls

What this Trial Is About

This research aims to understand how food affects heart and metabolic health in men with and without spinal cord injury SCI. The study focuses on men who are physically inactive and weight stable, comparing those with chronic high-level spinal cord injuries to those without. It is conducted by the University of Miami and examines how different meals impact energy use and hunger. Participants will be randomly assigned to one of three groups, each receiving a standardized meal with a different level of nutrient modification low, moderate, or high. Each participant will attend one visit per week over three weeks, consuming a 500-gram meal during each visit. Visits last about six hours, and the study also includes a control meal condition with a 600-700 gram standardized meal served at all visits. During the study, researchers will measure diet-induced thermogenesis, hunger using a visual scale, and the amount of food consumed after the meals. Data will be collected during each intervention visit over the three-week period. Participants will be monitored for up to three weeks, with assessments focusing on how their bodies process food and how hungry they feel following each meal.

Food Intake and Thermogenesis in High Spinal Cord Injury