Actively Recruiting

Phase Not Applicable
Age: 6Years - 16Years
All Genders
NCT05734261

Forced Oscillations Technique During a Metacholine Test in Children

Led by University Hospital, Montpellier · Updated on 2023-09-13

112

Participants Needed

1

Research Sites

172 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Asthma is the most common chronic lung disease in children. It affects more than 1 in 10 children in France. The methacholine bronchial challenge test (MBT) is indicated to assess the probability of asthma suggested by clinical symptoms by measuring the forced expiratory volume in one second (FEV1), after inhalation of a cumulative dose of methacholine. In children, the measurement of FEV1 requires a high level of cooperation from the child, which can be the source of false negatives or no result if this is not obtained. The objective of this study is to evaluate if the measurement of the respiratory function by the forced oscillations technique, allows to predict the variation of the FEV1 obtained

CONDITIONS

Official Title

Forced Oscillations Technique During a Metacholine Test in Children

Who Can Participate

Age: 6Years - 16Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age between 6 and 16 years
  • Forced expiratory volume in one second (FEV1) greater than 60%
  • Child referred for a methacholine bronchial challenge test to evaluate nonspecific bronchial hyperactivity
  • Child stopped inhaled corticosteroid treatment for at least 3 weeks
  • Oral consent given by the child and at least one legal representative
  • Child covered by or benefiting from a social security plan
Not Eligible

You will not qualify if you...

  • Use of short-acting beta-adrenergic bronchodilator within 6 hours or anticholinergic bronchodilator within 12 hours
  • Use of long-acting beta-adrenergic bronchodilator approved for children within the past 36 hours
  • Upper or lower respiratory tract infection within 3 weeks prior to inclusion
  • Epilepsy under treatment
  • Participation in another interventional study that may affect respiratory function
  • Patient unable to give consent or considered vulnerable

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

CHU de Montpellier

Montpellier, France

Actively Recruiting

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Research Team

S

Stefan MATECKI, MD

CONTACT

A

Anne REQUIRAND

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

DIAGNOSTIC

Number of Arms

1

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