Actively Recruiting

Phase 2
Age: 18Years +
All Genders
NCT05674396

3-5 FrAction Stereotactic Body Radiation Therapy for Palliation of Head and Neck Squamous Cell Carcinoma: the FAST Phase II Randomized Trial

Led by M.D. Anderson Cancer Center · Updated on 2026-02-19

108

Participants Needed

1

Research Sites

221 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

To learn if it is effective to use advanced radiation treatment techniques (stereotactic radiation or "SBRT") to safely deliver a strong dose of radiation to your tumor in a shorter period of time than would typically be feasible with traditional methods.

CONDITIONS

Official Title

3-5 FrAction Stereotactic Body Radiation Therapy for Palliation of Head and Neck Squamous Cell Carcinoma: the FAST Phase II Randomized Trial

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 or older
  • Willing to provide informed consent
  • Histologically confirmed squamous cell carcinoma
  • Primary tumor site in the head and neck, including oral cavity, oropharynx, nasopharynx, hypopharynx, larynx, salivary gland, cutaneous subsites, or unknown primary site
  • Ineligible for curative intent treatment after multidisciplinary evaluation
  • Prior therapy including radiation, surgery, or systemic therapy is permitted unless further radiation is inappropriate
  • Metastatic disease is permitted
Not Eligible

You will not qualify if you...

  • Contraindications to radiotherapy
  • Pregnant or lactating women

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

M D Anderson Cancer Center

Houston, Texas, United States, 77030

Actively Recruiting

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Research Team

J

Jay Reddy, MD,PHD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

2

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