Actively Recruiting
Fractional Flow Reserve Guided Immediate Versus Staged Complete Myocardial Revascularization in Patients With ST-segment Elevation Myocardial Infarction With Multivessel Disease (Future Study)
Led by RenJi Hospital · Updated on 2023-12-04
840
Participants Needed
1
Research Sites
263 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
It is a prospective, multicenter, randomised controlled, open-label, blinded endpoint assessment trial, to compare the strategy of immediate complete revascularisation and staged complete revascularisation in ST-segment-elevation myocardial infarction patients with multivessel coronary disease.
CONDITIONS
Official Title
Fractional Flow Reserve Guided Immediate Versus Staged Complete Myocardial Revascularization in Patients With ST-segment Elevation Myocardial Infarction With Multivessel Disease (Future Study)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 years or older
- Presenting with STEMI and multivessel coronary disease with successful primary PCI of the culprit lesion
- Multivessel disease defined as at least one non-culprit artery with diameter 2.5 mm or more and at least 50% blockage by visual estimation
- Ability to sign informed consent before participating in the study
You will not qualify if you...
- Received thrombolytic therapy
- Cardiac shock or systolic blood pressure less than 90 mmHg
- History of old myocardial infarction
- Left main artery lesion or chronic total occlusion lesions in non-infarct related vessels
- PCI in the previous 30 days or previous coronary artery bypass grafting
- Unable to give informed consent or life expectancy less than 1 year
- Severe renal dysfunction with creatinine clearance less than 30 ml/min, liver dysfunction, or thrombocytopenia
- Severe valve disease, hypertrophic cardiomyopathy, restrictive cardiomyopathy, or primary pulmonary hypertension
- Currently participating in another study that may affect the primary endpoint
- Pregnant or breastfeeding women
- Known allergy to drugs used in the study
- Unable to comply with trial protocol or follow-up requirements or if participation may result in greater risks
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Renji Hospital Affiliated to Shanghai Jiao Tong University School of Medicine
Shanghai, China
Actively Recruiting
Research Team
J
Jun Pu, MD, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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