Actively Recruiting
Impact of Clinical Frailty Scale on Morbidity and Mortality in Older Adults Diagnosed With Pneumonia in the Emergency Department: A Prospective Observational Cohort Study
Led by Ege University · Updated on 2026-03-02
150
Participants Needed
1
Research Sites
4 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Pneumonia is a leading cause of death from infection among older adults. This research aims to study how well the Clinical Frailty Scale (CFS), which measures a person's frailty or vulnerability, can predict death and illness in patients aged 65 and older who come to the emergency department with pneumonia. The study also evaluates whether adding frailty assessment to existing pneumonia severity scores improves predictions of outcomes. The study is a prospective observational cohort conducted at a tertiary university hospital emergency department. Participants aged 65 or older with pneumonia diagnosed by clinical and radiological means will be enrolled. Frailty will be assessed at the bedside using the 9-point Clinical Frailty Scale, and data including demographics, comorbidities, vital signs, and Pneumonia Severity Index (PSI) scores will be collected. The research compares frailty scores at presentation with baseline frailty before illness onset. Participants will be monitored for in-hospital mortality during their admission and for mortality within 30 days. Secondary outcomes include admission to intensive care and need for mechanical ventilation. Researchers will analyze if the Clinical Frailty Scale independently predicts these outcomes and if combining frailty with existing severity scores improves prognostic accuracy.
CONDITIONS
Brief Title
Frailty and Outcomes in Older Emergency Department Patients With Pneumonia
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 65 years or older
- Clinical and radiological diagnosis of pneumonia in the emergency department
- Ability to provide informed consent or have a legal representative provide consent
- Availability of a caregiver or relative able to describe baseline functional status
You will not qualify if you...
- Presentation with cardiopulmonary arrest or ongoing cardiopulmonary resuscitation at admission
- Confirmed COVID-19 pneumonia
- Inability to obtain reliable baseline functional history due to absence of an informant
- Refusal to provide informed consent
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - At emergency department presentation
Participants undergo assessment including the Clinical Frailty Scale performed at emergency department presentation to evaluate frailty and baseline functional status.
1 visit (in-person)
Duration - Up to 30 days after hospital admission
Participants are observed for outcomes such as in-hospital mortality and 30-day mortality following pneumonia diagnosis.
Assessments during hospital stay and follow-up up to 30 days
Trial Site Locations
Total: 1 location
1
Özge Can
Izmir, Bornova, Turkey (Türkiye), 35100
Actively Recruiting
Research Team
Ö
Özlem İnci, MD
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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