Actively Recruiting
Study of Frailty in Adults with Gastrointestinal Cancer Undergoing Major Surgery
Led by The Guthrie Clinic · Updated on 2026-04-29
100
Participants Needed
2
Research Sites
52 weeks
Total Duration
AI-Summary
What this Trial Is About
This research focuses on patients with gastrointestinal cancer who are scheduled to undergo major surgery. The study aims to identify cancer patients who might be at risk for frailty, a condition common in older adults characterized by symptoms such as weight loss, weakness, fatigue, low activity, slow walking, and other health issues. The study seeks to describe how often frailty occurs in these surgical cancer patients and to see if frailty is linked to problems following major surgery. Participants will complete a frailty survey called the Clinical Risk Analysis Index RAI-C before surgery to assess their frailty status. They will also have about 10 ml 2 teaspoons of blood drawn prior to surgery for various blood tests, including complete blood count CBC, vitamin A, creatinine, C-Reactive Protein CRP, DHEA, albumin, and prealbumin. The study involves reviewing medical records to gather further information. During the study, participants will complete the survey and provide a blood sample before their surgery. Researchers will measure the percentage of patients considered frail based on RAI-C scores of 21 or higher before surgery. They will also monitor adverse outcomes within 30 days after the surgery. The study involves observation and data collection without administering any treatment, and participants involvement will last through the preoperative and 30-day postoperative periods.
CONDITIONS
Brief Title
Frailty in Patients With Gastrointestinal Cancer Who Are Undergoing Major Surgery
Research Team
B
Burt Cagir, MD
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