Actively Recruiting

Phase Not Applicable
Age: 65Years +
All Genders
NCT03824106

Frailty Rehabilitation

Led by McMaster University · Updated on 2025-07-06

324

Participants Needed

1

Research Sites

173 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Frailty is an important clinical state that contributes to falls, hospitalization, institutionalization and death. When an individual simultaneously has many health problems, a frailty "tipping point" may be triggered by even a minor stressful event such as adding a new drug or urinary tract infection. Our research suggests that approximately 23% of Canadians over age 65 are frail, and by age 85 this estimate increases to over 40%. As we learn more about frailty and its consequences, there is an urgent need to develop community-based interventions that will prevent or delay frailty in older adults. Our proposed study will examine if frailty rehabilitation program is an effective community-based intervention to promote healthy aging. The primary objective of our study is to determine if 4-month frailty rehabilitation improves physical function compared with control and exercise alone in community-dwelling older adults living with frailty and sarcopenia. Secondary objectives of our study are to determine if 4-months of frailty rehabilitation can improve functional abilities and reduce healthcare utilization during a 6-month follow-up period compared with control and exercise alone. Results will translate the first Canadian model of frailty and sarcopenia rehabilitation and management.

CONDITIONS

Official Title

Frailty Rehabilitation

Who Can Participate

Age: 65Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Community-dwelling adults aged 65 years or older
  • Able to independently walk 25 meters with or without a walking aid
  • At high risk for mobility disability or functional limitations
  • Received medical clearance to participate
  • Able to arrange transportation to YMCA up to twice per week
  • Proof of full COVID-19 vaccination and identification
Not Eligible

You will not qualify if you...

  • Unable to speak or understand English
  • Currently attending a group exercise program
  • Currently enrolled in a drug optimization study or program
  • Taking protein supplements daily
  • Significant cognitive impairment affecting ability to follow two-step commands
  • Receiving palliative or end-of-life care
  • Diagnosed with unstable angina or heart failure
  • Unable to attend more than 80% of the trial sessions

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

McMaster University - St. Peter's Hospital

Hamilton, Ontario, Canada, L8M1W9

Actively Recruiting

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Research Team

S

Sherri Smith

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

QUADRUPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

PREVENTION

Number of Arms

3

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Frailty Rehabilitation | DecenTrialz