Actively Recruiting
Led by Medical University of Silesia · Updated on 2023-04-12
1000
Participants Needed
1
Research Sites
156 weeks
Total Duration
Researchers are investigating how frailty affects the immediate and long-term outcomes of invasive treatments for coronary artery disease in older adults aged 65 and above. The study aims to validate the Fried frailty scale and the instrumental activities of daily living (IADL) scale as tools to predict patient outcomes. This research focuses on patients admitted with stable, unstable, or acute coronary syndromes to better understand the role of frailty in their care. Participants include those with stable angina, unstable angina, non-ST elevation myocardial infarction (NSTEMI), and ST elevation myocardial infarction (STEMI). Based on coronary angiography results, a heart team decides the best treatment approach, which may be medical management, percutaneous angioplasty, or bypass grafting. Most STEMI patients receive primary percutaneous coronary intervention. The study observes treatments during hospital admission and treatment decisions by the heart team. During the hospital stay, frailty is assessed using the Fried phenotype and IADL scales before discharge, typically around day 4. Researchers track results of the invasive treatments and any complications such as heart attacks during procedures, kidney injury from contrast dye, and bleeding. Long-term outcomes including mortality, stroke, heart failure, reintervention, and hospital readmission are monitored for up to three years. This study aims to help personalize risk assessment and improve care for frail elderly patients with coronary artery disease.
CONDITIONS
Frailty Syndrome in Daily Practice of Interventional Cardiology Ward
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Complete this quick 3-step screening to check your eligibility
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Up to hospital discharge, on average 4 days
Participants undergo coronary angiography to evaluate their coronary artery disease and determine appropriate treatment.
1 hospital stay with assessments
Duration - Up to 36 months
Participants are monitored for major cardiovascular events following their interventional treatment or medical management.
Periodic follow-up visits over 36 months
Total: 1 location
1
II Dept. of Cardiology in Zabrze Medical University of Silesia
Zabrze, Upper Silesia, Poland, 41-800
Actively Recruiting
A
Andrzej R Tomasik, M.D. Ph.D., FESC
E
Ewa Nowalany-Kozielska, Prof.
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
4
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Ewa Wołoszyn-Horák, Robert Salamon, Katarzyna Chojnacka...
https://pubmed.ncbi.nlm.nih.gov/32000408