Study on Frailty and Outcomes in Older Adults Undergoing Treatment for Coronary Artery Disease

What this Trial Is About

Researchers are investigating how frailty affects the immediate and long-term outcomes of invasive treatments for coronary artery disease in older adults aged 65 and above. The study aims to validate the Fried frailty scale and the instrumental activities of daily living IADL scale as tools to predict patient outcomes. This research focuses on patients admitted with stable, unstable, or acute coronary syndromes to better understand the role of frailty in their care. Participants include those with stable angina, unstable angina, non-ST elevation myocardial infarction NSTEMI, and ST elevation myocardial infarction STEMI. Based on coronary angiography results, a heart team decides the best treatment approach, which may be medical management, percutaneous angioplasty, or bypass grafting. Most STEMI patients receive primary percutaneous coronary intervention. The study observes treatments during hospital admission and treatment decisions by the heart team. During the hospital stay, frailty is assessed using the Fried phenotype and IADL scales before discharge, typically around day 4. Researchers track results of the invasive treatments and any complications such as heart attacks during procedures, kidney injury from contrast dye, and bleeding. Long-term outcomes including mortality, stroke, heart failure, reintervention, and hospital readmission are monitored for up to three years. This study aims to help personalize risk assessment and improve care for frail elderly patients with coronary artery disease.

Frailty Syndrome in Daily Practice of Interventional Cardiology Ward