Actively Recruiting

All Genders
ID06739239

French COhoRte Extra-Vascular Implantable CardiovErter DefibrillatoR Evaluation of Long-Term Safety and Performance

Led by Paris Sudden Death Expertise Center · Updated on 2024-12-20

1000

Participants Needed

1

Research Sites

360 weeks

Total Duration

On this page

Sponsors

P

Paris Sudden Death Expertise Center

Lead Sponsor

E

European Georges Pompidou Hospital

Collaborating Sponsor

AI-Summary

What this Trial Is About

Implantable cardioverter-defibrillators (ICDs) help reduce the risk of sudden cardiac death in patients at high risk. This study focuses on the extravascular cardioverter-defibrillator (EV-ICD), a newer device with a lead placed under the sternum. The EV-ICD delivers pacing and defibrillation similar to traditional ICDs but may offer advantages in safety and design. Previous research showed safe implantation and effective treatment of arrhythmias, but long-term data from broader use are limited. The study evaluates the use of the EV-ICD across France by collecting information on all implantations nationwide. The device involves implanting a pulse generator near the left midaxillary line and positioning the lead in the substernal space. This design aims to provide pause-prevention pacing, antitachycardia pacing, and defibrillation energy like conventional ICDs. Participants will be followed for about five years to monitor outcomes including appropriate therapies delivered by the device, early and late complications related to the EV-ICD, and overall mortality. The study gathers real-world evidence on the long-term safety and effectiveness of the EV-ICD, providing valuable insights from a wide range of patients receiving this treatment in clinical practice.

CONDITIONS

Official Title

French COhoRte Extra-Vascular Implantable CardiovErter DefibrillatoR

Who Can Participate

All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • All patients undergoing EV-ICD implantation
Not Eligible

You will not qualify if you...

  • Refusal of consent

AI-Screening

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Trial Site Locations

Total: 1 location

1

European Georges Pompidou Hospital

Paris, France, 75015

Actively Recruiting

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Research Team

E

Eloi MARIJON, MD, PhD

F

Fawzi KERKOURI, MD, MPH

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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