Actively Recruiting
French-German Cohort Study to Determine Factors Associated With Weight Loss in Amyotrophic Lateral Sclerosis
Led by University Hospital, Limoges · Updated on 2024-11-25
1000
Participants Needed
7
Research Sites
262 weeks
Total Duration
On this page
Sponsors
U
University Hospital, Limoges
Lead Sponsor
N
National Research Agency, France
Collaborating Sponsor
AI-Summary
What this Trial Is About
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease. Studies have shown the importance of weight loss at the time of diagnosis and during the progression of the disease. However, the pathophysiological mechanisms behind weight loss remain unknown. Identifying these mechanisms could make it possible to propose an effective therapeutic strategy against weight loss for ALS patients, which could improve their survival and quality of life. In this context, the investigators are proposing an innovative multidisciplinary project aimed at structuring a large Franco-German cohort to identify the markers associated with weight loss in ALS. Participants will undergo high quality standard care for ALS patients. In addition, participants will be asked to respond different questionnaires and blood samples will be taken for analysis to identify biological markers.
CONDITIONS
Official Title
French-German Cohort Study to Determine Factors Associated With Weight Loss in Amyotrophic Lateral Sclerosis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosed with definite, probable, probable laboratory-supported, or possible ALS according to El Escorial revised and Gold Coast criteria at the time of diagnosis
- Incident ALS cases identified and followed-up in designated ALS and Motor Neuron Diseases Referral Centres in France and Germany
- Signed informed consent form
- Adults aged over 18 years
You will not qualify if you...
- Unable to understand the protocol requirements
- Unable to sign or comprehend the informed consent form due to cognitive issues
- Refusal to accept Riluzole therapy during follow-up
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 7 locations
1
CHU de Lille
Lille, France, 59037
Not Yet Recruiting
2
Limoges University Hospital
Limoges, France, 87042
Actively Recruiting
3
Hôpital de la Timone
Marseille, France, 13005
Not Yet Recruiting
4
Hôpital Gui Chauliac
Montpellier, France, 34295
Not Yet Recruiting
5
CHU de Nice
Nice, France, 06001
Not Yet Recruiting
6
Hôpital de la Pitié Salpêtrière
Paris, France, 75013
Not Yet Recruiting
7
CHU de Tours
Tours, France, 37044
Not Yet Recruiting
Research Team
P
Philippe COURATIER, Pr
CONTACT
A
Andrea ERAZO ALEMAN, Dr
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
OTHER
Number of Arms
1
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