Actively Recruiting

Age: 0Days +
All Genders
NCT04177134

French Register of Patients With Spinal Muscular Atrophy

Led by Assistance Publique - Hôpitaux de Paris · Updated on 2025-04-06

1000

Participants Needed

1

Research Sites

469 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The primary objectives of the study are to obtain clinically meaningful data on survival and outcomes of all the patients with spinal muscular atrophy (SMA) 5q types 1 through 4 (according to international classification), being followed in the reference centers of the disease in France between September 1, 2016 and August 31, 2024. The registry will collect retrospectively and prospectively the longitudinal data of the long-term follow-up for child and adult patients, under real life conditions of current medical practice, in order to document the clinical evolution of patients (survival, motor, respiratory, orthopedic and nutritional), the conditions of use of the treatments, the mortality rates of treated and untreated patients, the tolerance of the treatments, adverse events in order to better define their places in the therapeutic strategy.

CONDITIONS

Official Title

French Register of Patients With Spinal Muscular Atrophy

Who Can Participate

Age: 0Days +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Genetically confirmed SMA 5q patients of types 1 through 4 treated in reference centers in France between September 1, 2016 and August 31, 2024
  • Signed informed consent form for prospective participation
  • Non-opposition information given for retrospective data
  • Covered by health insurance
Not Eligible

You will not qualify if you...

  • SMA types other than 5q
  • Under legal guardianship or curatorship
  • Unable to understand French language

AI-Screening

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Trial Site Locations

Total: 1 location

1

Unité neuromusculaire, Service de Neurologie et Réanimation Pédiatrique, (French neuromuscular reference network (FILNEMUS), Hôpital Raymond Poincaré,

Garches, France, 92380

Actively Recruiting

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Research Team

S

Susana Quijano-Roy, MD, PhD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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French Register of Patients With Spinal Muscular Atrophy | DecenTrialz