Actively Recruiting

Phase Not Applicable
Age: 12Years - 17Years
All Genders
NCT06649552

French Validation of Schizophrenia Proneness Instrument- Child Youth

Led by Centre Psychothérapique de Nancy · Updated on 2026-04-24

52

Participants Needed

3

Research Sites

102 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The clinical concept of a at risk mental state of developing psychosis is based on the identification of attenuated psychotic symptoms during the prodromal phase of psychoses (Schmidt et al., 2015). Early detection and support of these symptoms can delay the risk of transition to a first psychotic episode (van der Gaag, van den Berg, \& Ising, 2019). The Basic Symptom approach enables detection at the earliest stage of the prodromal phase. It postulates that subtle, subjective manifestations predating attenuated psychotic symptoms are present very early in the prodromal phase of psychosis and also have predictive value for the risk of developing psychosis (F. Schultze-Lutter, 2009). Basic symptoms are assessed using the Schizophrenia Proneness Instrument, available in an adult (SPI-A) and child/adolescent (SPI-CY) version. These scales are part of the international recommendations for the assessment of patients with a Clinical State at High Risk of Psychosis (CHR-P) (Schmidt et al., 2015; F Schultze-Lutter et al., 2015). The SPI-A is validated in French under the name "Outil d'Evaluation du Risque Schizophrénique version adulte (OERS-A)" (Schultze-Lutter et al., 2007. French translation by JR. Teyssier with the collaboration of F. Gamma and P. Loulergue), but no French version of the SPI-CY has yet been validated. In collaboration with Dr. Frauke Schultze-Lutter, the investigators have recently published a French translation of the SPI-CY (Schizophrenia Predisposition Instrument - Version for Children and Adolescents, F. Schultze-Lutter, M. Marshall, E. Koch, 2021. French translation by F. Bernardin and C. Dondé). This French translation must now be validated to ensure the inter-rater fidelity of the interview. We therefore propose to study the inter-rater reliability of the French version of the SPI-CY by comparing ratings between clinicians who have undergone training in basic symptoms and in administering the SPI-A and SPI-CY tools by Dr. Schultze-Lutter. This validation will be carried out by comparing, on the one hand, the rating of the SPI-CY by a clinician A who has administered it to the patient and, on the other hand, the blind rating of a clinician B on the basis of the interview recorded by clinician A with his patient. The investigators will also explore the links between the SPI-CY and other clinical scales such as the Multisensory Hallucination SCale (MHASC) (Demeulemeester et al., 2015), the Prodromal Questionnaire 16 (PQ-16) (Lejuste et al., 2021), the Audiograph (Giersch, Huard, Park, \& Rosen, 2021) and the Perceptual and Cognitive Aberrations (PCA) (McDonald et al., 2019).

CONDITIONS

Official Title

French Validation of Schizophrenia Proneness Instrument- Child Youth

Who Can Participate

Age: 12Years - 17Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients aged 12 to 17 years and 11 months followed at CLIP-Ado Nancy, CH Alpes-Isère, or CHRU Lille for suspected risk of psychosis as determined by CAARMS or SPI-CY scales
  • Affiliated with or beneficiary of a social security scheme
  • Native French speaker
  • Adolescent informed about the study, received information, and not objecting to participation
  • At least one parent or guardian informed about the study, received information, and not objecting to participation
  • Consent given by adolescent and at least one parent for audio recording of the SPI-CY interview
Not Eligible

You will not qualify if you...

  • Pregnant woman, woman in labor, or nursing mother
  • Person deprived of liberty by judicial or administrative decision
  • Person in a life-threatening emergency
  • Impairment preventing participation or understanding study information
  • Substance abuse or dependence per DSM V criteria, excluding cannabis

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
+1

Trial Site Locations

Total: 3 locations

1

CHRU Lille

Lille, France, 59037

Not Yet Recruiting

2

Centre Psychothérapique de Nancy

Nancy, France, 54521

Actively Recruiting

3

CH Alpes-Isère

Saint-Egrève, France, 38120

Actively Recruiting

Loading map...

Research Team

F

Florent BERNARDIN

CONTACT

T

Tatiana DABROWSKI

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

DIAGNOSTIC

Number of Arms

1

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here