Actively Recruiting
French Validation of Schizophrenia Proneness Instrument- Child Youth
Led by Centre Psychothérapique de Nancy · Updated on 2026-04-24
52
Participants Needed
3
Research Sites
102 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The clinical concept of a at risk mental state of developing psychosis is based on the identification of attenuated psychotic symptoms during the prodromal phase of psychoses (Schmidt et al., 2015). Early detection and support of these symptoms can delay the risk of transition to a first psychotic episode (van der Gaag, van den Berg, \& Ising, 2019). The Basic Symptom approach enables detection at the earliest stage of the prodromal phase. It postulates that subtle, subjective manifestations predating attenuated psychotic symptoms are present very early in the prodromal phase of psychosis and also have predictive value for the risk of developing psychosis (F. Schultze-Lutter, 2009). Basic symptoms are assessed using the Schizophrenia Proneness Instrument, available in an adult (SPI-A) and child/adolescent (SPI-CY) version. These scales are part of the international recommendations for the assessment of patients with a Clinical State at High Risk of Psychosis (CHR-P) (Schmidt et al., 2015; F Schultze-Lutter et al., 2015). The SPI-A is validated in French under the name "Outil d'Evaluation du Risque Schizophrénique version adulte (OERS-A)" (Schultze-Lutter et al., 2007. French translation by JR. Teyssier with the collaboration of F. Gamma and P. Loulergue), but no French version of the SPI-CY has yet been validated. In collaboration with Dr. Frauke Schultze-Lutter, the investigators have recently published a French translation of the SPI-CY (Schizophrenia Predisposition Instrument - Version for Children and Adolescents, F. Schultze-Lutter, M. Marshall, E. Koch, 2021. French translation by F. Bernardin and C. Dondé). This French translation must now be validated to ensure the inter-rater fidelity of the interview. We therefore propose to study the inter-rater reliability of the French version of the SPI-CY by comparing ratings between clinicians who have undergone training in basic symptoms and in administering the SPI-A and SPI-CY tools by Dr. Schultze-Lutter. This validation will be carried out by comparing, on the one hand, the rating of the SPI-CY by a clinician A who has administered it to the patient and, on the other hand, the blind rating of a clinician B on the basis of the interview recorded by clinician A with his patient. The investigators will also explore the links between the SPI-CY and other clinical scales such as the Multisensory Hallucination SCale (MHASC) (Demeulemeester et al., 2015), the Prodromal Questionnaire 16 (PQ-16) (Lejuste et al., 2021), the Audiograph (Giersch, Huard, Park, \& Rosen, 2021) and the Perceptual and Cognitive Aberrations (PCA) (McDonald et al., 2019).
CONDITIONS
Official Title
French Validation of Schizophrenia Proneness Instrument- Child Youth
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients aged 12 to 17 years and 11 months followed at CLIP-Ado Nancy, CH Alpes-Isère, or CHRU Lille for suspected risk of psychosis as determined by CAARMS or SPI-CY scales
- Affiliated with or beneficiary of a social security scheme
- Native French speaker
- Adolescent informed about the study, received information, and not objecting to participation
- At least one parent or guardian informed about the study, received information, and not objecting to participation
- Consent given by adolescent and at least one parent for audio recording of the SPI-CY interview
You will not qualify if you...
- Pregnant woman, woman in labor, or nursing mother
- Person deprived of liberty by judicial or administrative decision
- Person in a life-threatening emergency
- Impairment preventing participation or understanding study information
- Substance abuse or dependence per DSM V criteria, excluding cannabis
AI-Screening
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Trial Site Locations
Total: 3 locations
1
CHRU Lille
Lille, France, 59037
Not Yet Recruiting
2
Centre Psychothérapique de Nancy
Nancy, France, 54521
Actively Recruiting
3
CH Alpes-Isère
Saint-Egrève, France, 38120
Actively Recruiting
Research Team
F
Florent BERNARDIN
CONTACT
T
Tatiana DABROWSKI
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
DIAGNOSTIC
Number of Arms
1
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