Incidence and Risk Factors of Postoperative Nausea and Vomiting (PONV) During Elective C-Section Under Spinal Anesthesia With Multimodal Antiemetic Prophylaxis

What this Trial Is About

Researchers are studying the frequency and risk factors of nausea and vomiting after planned caesarean sections performed under spinal anesthesia. This observational study focuses on patients receiving intrathecal morphine and multimodal antiemetic preventive treatment to understand how often these symptoms occur and what might increase the risk. It aims to provide detailed insights into postoperative nausea and vomiting during elective caesarean delivery. Participants will undergo their caesarean section following the standard care protocol, including spinal anesthesia with intrathecal morphine and preventive anti-nausea medications. There are no experimental treatments or interventions beyond this usual care. The study will observe and record nausea and vomiting from the time of surgery through the first 24 hours post-operation. Patients will be asked specific questions about nausea and vomiting shortly after surgery in the recovery room and during two additional visits within the first 24 hours following their caesarean. The main outcome measured is the occurrence of nausea and vomiting during this period, while secondary outcomes focus on identifying risk factors. This study is sponsored by the University of Liege and will continue until April 2026.

Frequency of Occurrence and Risk Factors of Postoperative Nausea and Vomiting During Elective C-section Under Spinal Anesthesia With Preventive Medication