Actively Recruiting

Phase 4
Age: 18Years +
All Genders
NCT06673602

Fufang Congrong Yizhi Capsules (FCYC) of Cognitive Impairment After Intracerebral Hemorrhage

Led by Qinhuangdao Hospital of Traditional Chinese Medicine · Updated on 2024-11-06

200

Participants Needed

6

Research Sites

86 weeks

Total Duration

On this page

Sponsors

Q

Qinhuangdao Hospital of Traditional Chinese Medicine

Lead Sponsor

K

Kaifeng Third People's Hospital

Collaborating Sponsor

AI-Summary

What this Trial Is About

This is a randomized, controlled clinical study conducted across multiple centers. The neurosurgical robot can be used to treat patients with acute intracerebral hemorrhage (ICH). Establish a cohort comprising 200 participants with cognitive impairment after robot-assisted neurosurgery treatment for ICH. Two hundred participants are randomly assigned to either an experimental group (n=100) or a control group (n=100). The experimental group receive conventional treatment and oral administration of Fufang Congrong Yizhi Capsules (FCYC) for 12 weeks, while the control group receive only conventional treatment. The object of the current study is 1) to observe the security and effectiveness of FCYC and 2) to decipher the contributing factors to cognitive impairment after robot-assisted neurosurgery treatment for intracerebral hemorrhage.

CONDITIONS

Official Title

Fufang Congrong Yizhi Capsules (FCYC) of Cognitive Impairment After Intracerebral Hemorrhage

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosed with intracerebral hemorrhage (ICH) treated using neurosurgical robot
  • Diagnosed with post-stroke cognitive impairment (PSCI)
  • Meet traditional Chinese medicine diagnosis of deficiency of liver and kidney and phlegm and stagnant blood obstructing meridians pattern
  • Aged 18 years or older
  • Any gender
  • At least 2 weeks since onset of ICH
  • Conscious with sufficient visual and auditory recognition to undergo neuropsychological evaluation
  • Provide informed consent
Not Eligible

You will not qualify if you...

  • Diagnosed with other types of dementia besides vascular dementia, such as Alzheimer's, Lewy body dementia, or frontotemporal dementia
  • Have systemic diseases affecting cognitive function, including Parkinson's disease, normal pressure hydrocephalus, brain tumor, encephalitis, thyroid dysfunction, severe anemia, syphilis, or AIDS
  • Unable to participate in examination due to severe visual or auditory impairment, apraxia, aphasia, or neurological abnormalities
  • Have communication difficulties or mental illness
  • Have depression with Hamilton Depression Scale score 17 or higher
  • Diagnosed with alcohol or drug dependency within past 6 months
  • Have severe liver, kidney, or heart failure or other serious primary diseases
  • Are pregnant, breastfeeding, or planning pregnancy

AI-Screening

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Trial Site Locations

Total: 6 locations

1

Second Affiliated Hospital of Tsinghua University

Beijing, Beijing Municipality, China, 100040

Actively Recruiting

2

Qinhuangdao Hospital of Traditional Chinese Medicine

Qinhuangdao, Hebei, China, 066000

Actively Recruiting

3

Kaifeng Third People's Hospital

Kaifeng, Henan, China, 475000

Actively Recruiting

4

Shandong Public Health Clinical Center

Jinan, Shandong, China, 250102

Actively Recruiting

5

Weifang Hospital of Traditional Chinese Medicine

Weifang, Shandong, China, 261041

Actively Recruiting

6

Kunming Sanbo Brain Hospital

Kunming, Yunnan, China, 650100

Actively Recruiting

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Research Team

Q

Qihui Zhang, MD. PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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