Actively Recruiting
Full-Avoidance vs. Permissive/Regulated Drinking & Outcomes On Fibrillation
Led by University of California, San Francisco · Updated on 2025-12-23
100
Participants Needed
2
Research Sites
223 weeks
Total Duration
On this page
Sponsors
U
University of California, San Francisco
Lead Sponsor
N
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Collaborating Sponsor
AI-Summary
What this Trial Is About
The goal of this study is to assess the short-term effects of minimal and moderate drinking on atrial fibrillation (AFib) episodes in a real-world population diagnosed with 'come-and-go'/paroxysmal AFib. The question it aims to answer is: Is there a greater occurrence of AFib episodes when participants are allowed to consume alcohol according to random assignment? Participants will: * Be given daily random assignments to avoid or not to avoid alcohol * Wear an adhesive electrocardiographic (ECG) heart monitor * Wear a wrist-worn fitness tracker * Wear an anklet transdermal alcohol monitor * Wear an adhesive glucose monitor * Complete morning and evening surveys daily Participants may be compensated up to $50 for full completion of the study. This study can be done in-person or remote.
CONDITIONS
Official Title
Full-Avoidance vs. Permissive/Regulated Drinking & Outcomes On Fibrillation
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Comfortable reading and writing in English
- Have a smartphone and willing and able to use the Eureka mobile application
- Currently diagnosed with paroxysmal AFib without a plan to change their AFib management during the two-week monitoring period
- At least one episode of AFib in the past month OR, in the judgement of a healthcare provider, could potentially have one episode of AF in the next month
- Drank alcohol at least 1 day/week on average in the past month
- Willing and able to be randomly assigned daily to avoid or not avoid drinking alcohol over a 2-week period
- Willing and able to provide written informed consent
You will not qualify if you...
- Only post-operative AFib
- Greater than 40% ventricular pacing
- History of alcohol addiction or abuse determined by self-reported history or AUDIT-C score
- Intolerance to alcohol
- History of liver disease
- Currently incarcerated
- Currently pregnant or trying to get pregnant
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 2 locations
1
UCSF Medical Center at Parnassus
San Francisco, California, United States, 94143
Actively Recruiting
2
UCSF Medical Center at Mission Bay
San Francisco, California, United States, 94158
Actively Recruiting
Research Team
G
Gregory M Marcus, MD, MAS
CONTACT
H
Hannah H Oo, BS
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
OTHER
Number of Arms
2
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